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Re: Cam or anyone, Anafranil better for OCD?

Posted by Maniz on October 30, 2000, at 10:58:03

In reply to Cam or anyone, Anafranil better for OCD?, posted by Trish Baker on October 30, 2000, at 1:23:53


Just speculation.

I do not know if Celexa is a serotonin reuptake inhibitor which I think is the class of AD used for OCD.

Adrafinil is a alpha-1 adrenergic agonist (at least this is what I read as an explanation for its effect).

The AD Wellbutrin has noradrenaline reuptake inhibition effect besides serotonin (I am just using my memory,I am sure about NA but not Serotonin).

So if Adrafinil (I wonder what the chem name is) worked for you maybe Wellbutrin makes a better AD for you.

Just a thought, you should check.

I do not understand how a stimulant (like Adrafinil) has a calming effect. Some people report a calming effect from a mild stimulant like DMAE.

Have you ever tried DMAE (dimethylaminoethanol)?. It is a very safe an cheap amino acid available at any vitamin store which has a reported use for many ailments including ADD and OCD.
DMAE is a cholinergic (acetylcholine precursor). DMAE worked for people with low MAO (it seems some forms of depression are related to low MAO).

I also found this about adrenergics here

The Alfa-1-receptors stimulate the conversion of liver molecules to sugar molecules (glucogenolysis), resulting in more glucose in the blood. Alpha-1 also stimulates the consumption of oxygen (O2) by the cells and stimulates the conversion of fatty acid in blood to energy. All of these alpha-1 items result in more energy for the person. If the alpha-1 receptors are clogged (e.g. by a pesky heavy metal molecule), one would feel fatigued. The following things can clog NA alpha-1 receptors: antagonist drugs, lead, mercury, cadmium, sulfur-toxins, over 70,000 manmade chemicals, and several natural toxins.

Maybe another product than Adrafinil can have similar effects.

> I took Anafranil in the past for OCD and it did wonders for me. However, I had a relapse of my OCD after a lot of stress and quit taking it several years ago. Since then, I've tried a multitude of SSRI's, some okay, others bad. I'm currently on Celexa 30mg and Klonopin 1mg. Can one supplement Anafranil with Celexa or is it best just to be on one or the other. If I can supplement, do you usually take a minimum dose of each?
> Thanks,
> Trish




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