Posted by Rick on July 27, 2000, at 21:23:51
In reply to Re: Adrafinil and Liver Damage -- SLS » shar, posted by SLS on July 27, 2000, at 10:29:41
> Hi.
>
> From "unofficial" sources on the Internet (drug sales sites):
>
>
> --------------------------------------
>
>
> Safety
>
> Although adrafinil is generally regarded as quite safe, a few adverse effects have been reported with long-term use, including stomach pain, skin irritations, and a feeling of "inner tension." Long-term use has also been associated with occasional instances of elevated liver enzymes, specifically SGOT, SGPT, GGPT, and hepatic alkaline phosphatase. Thus, if you plan to use adrafinil for an extended period of time, we suggest you have your liver function tested to establish a baseline, and then after 3 months and again every 6 months thereafter. If abnormalities appear, reducing the dose or stopping the drug should permit a return to normal.
>
>
> -------------------------------------------------
>
> I was going to call the drug company directly, but I had trouble with the numbers as they were listed by them. I didn't have the opportunity to retry the numbers using the France country-code: 33. It is likely that you will find someone who speaks English.
>
> Adrafinil (Olmifon)
>
> Laboratoire L. LAFON
> Laboratoire Louis Lafon
> Siège
> 19, avenue du Pr Cadiot
> 94701 MAISONS-ALFORT
> Tél : 01.49.81.81.00
> www.lablafon.com
>
>
> LAFON
> Adresse : 20, rue Charles Martigny
> BP22
> 94701 MAISONS ALFORT
> Telephone : 01.49.81.81.00
> Telecopie : 01.48.98.13.72
>
>
> -------------------------------------------------
>
>
> > Scott,
> > I have ordered Adrafinil, and the posts on adrafinil and liver damage were a little worrisome to me. What was your final take on the situation?
> >
> > I take Effexor/Wellbu/Klonopin. All blood tests I've had (like for cholesteral but they check other things too) have been ok for liver. Think another one before starting Adraf. would be a good idea? My last blood test has been at least a year ago.
> >
> > Thanks for any info--
> > SharInterestingly, most of the enzymes listed above are NOT included in "standard" liver tests I've had. Indeed, different labs seem to test a different number of enzymes, although the only enzyme listed above that I've seen is alkaline phosphate.
My pdoc (who I'm beginning to wonder about...) say that only research labs can uncover most cases of liver damage caused by individual psychotropics or psychotropic combinations.
Rick
poster:Rick
thread:41468
URL: http://www.dr-bob.org/babble/20000717/msgs/41537.html