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history - Jennifer

Posted by Elizabeth on June 3, 2000, at 7:50:15

In reply to Re: Jennifer back 2 Scott-Nardil Aug, posted by Jennifer on June 1, 2000, at 4:59:25

> Mirapex does lower your blood pressure though, and since Nardil was originally for lowering blood pressure (and then when everyone was in a good mood, they found a new use for it!) you may get a double whammy of low b/p.

Nardil has always been used primarily for depression and anxiety. The first MAOI used for depression, iproniazid (Marsilid), was an anti-TB drug that was found to be a "mood elevator," which got people all interested in MAOIs as antidepressants. It was taken off the market because it tended to be hepatotoxic, but its cousin isoniazid (INH), which is not an MAOI of any significance, is still a first-line tx for TB.

There was an MAOI - Eutonyl (pargyline) - that popped up at some point and was used as an antihypertensive, but it's no longer available AFAIK.

BTW, I wouldn't necessarily trust anything a pharmacist said about MAOIs. IME, they tend to get a lot of things wrong, especially in regard to interactions; I pretty much feel I can count on them to parrot the PDR (though there are exceptions). I attribute this to a lack of real clinical experience.


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poster:Elizabeth thread:34894
URL: http://www.dr-bob.org/babble/20000603/msgs/35822.html