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Re: Jennifer back 2 Scott-Nardil Aug - Thanks

Posted by SLS on June 1, 2000, at 16:30:45

In reply to Re: Jennifer back 2 Scott-Nardil Aug, posted by Jennifer on June 1, 2000, at 4:59:25

> > Is there any way I can twist your arm and have you summarize their suggestions as what to use to supplement an MAO inhibitor?

> Ok, it took me 3 very long days to finally get back on line, sorry...but yes, my arm has been twisted. Hope this helps:


Hi Jennifer.

I really appreciate your reply. Use ice for the first three days, then alternate ice and heat for another five.

> Aumentation is adding 1 or more drugs which by themselves don't have established antidepressant effects. But, with another antidepressant can increase the reponsiveness. Combination therapy is the use of more than 1 antidepressant.

I was always a bit unclear about this distinction.

> They suggested several meds for "antidepressant augmentation" without being specific if it would interact with the Nardil. Lithium, Klonopin, and thryroid are all ok - as I am not dead,

LOL - Can you hear me?

> and I always research until I'm blue in the face before taking new meds.

I'll know who to ask from now on.

> Other recommendations were pindolol (Visken) and Mirapex-which I am unsure if they are safe with MAOI's.

It is.

> You'll need to ask a pharmacist on that one. Mirapex does lower your blood pressure though, and since Nardil was originally for lowering blood pressure (and then when everyone was in a good mood, they found a new use for it!) you may get a double whammy of low b/p. Good luck...maybe call a pharmacist on these, and then talk with your pdoc. Didn't he/she have any recommendations?
Or were they not trusted recommendations? Jen.

I have thrown a lot of crap at Parnate, but not Nardil. Obviously, these attempts have not been terribly successful. I am ALWAYS looking for new ideas, and this is probably one of the best places to find them. This is such a great pooling of the expertise of the psychiatrists treating us, not to mention the brilliance of their patients.

> PS: My old pdoc told me that if you discontinue Nardil, and then go back on later, 10% of the patients no longer respond, or respond poorly. I don't know if this is true. I do know I needed the higher dose when I went back on.

This often happens, although I don't know the statistics behind it. It is so tragic to see. I am an advocate of extended treatment periods. For a subgroup of us, treatment should be continued indefinitely. You may want to take inventory to see if you are eligible to join the club of which I am a member.

If someone has been taking Nardil and begins to experience "poop-out", sometimes stopping and restarting it will work to recapture a strong antidepressant response. I would say that it is prudent to try other strategies first.

Thanks again.

:-)


- Scott

 

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