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Re: Serzone

Posted by Noa on May 17, 2000, at 10:51:20

In reply to Re: Serzone, posted by Cindy W on May 17, 2000, at 9:21:16

One thing Serzone does well for me is to block the so-called "bad" serotonin receptors, ie, the ones that seem to be related to being agitated, antsy, twitchy, fidgety, and sleepless.

I find serzone to be slower/longer acting than trazodone was for me. With trazodone, I would take 25 mg and within an hour couldn't keep my eyes open. With serzone, I take 300 mg at around 6 pm or so, and am ready to sleep at 10. When I take it later than early evening , I am still fidgety when I get into bed and getting up in the morning is hell.

I still feel too much of the activating serotonin, and am thinking of shifting the effexor:serzone ratio even more. It had been 375:225 for a long time. Lately it has been 300:300. I can't tell how much antidepressent power the serzone has for me, because I did the impatient thing of increasing serzone and decreasing effexor at the same time. I am tempted to give a trial of adding up to 150 mg serzone in the morning.

Dove, I think the four times a day dose is inconvenient, but it might help in not knocking you out.The higher dose of serzone (300) does cause me more drowsiness about one hour after taking it than with the smaller dose. But it seems to even out after a while and not conk me out. Does anyone know if the sedation effects start to wear off at all after a while? Are they the same for morning doses as evening doses?


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