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Terry and Dove...Serzone Dosing

Posted by Aylese on May 17, 2000, at 9:44:28

In reply to ? for JohnL serzone dosing, posted by dove on May 17, 2000, at 8:54:11

Dove, Your Doctor is indeed knowledgeable if he is prescribing Serzone 4 times a day. It has a very short half-life of only 2-4 hours. ( It is very short-acting.) General directions are for dosing twice a day, which leaves a huge gap when you aren't being helped. Four times a day keeps your Serzone level more steady. It is a terrible nusience four times a day, but I bought an alarm wrist watch to remind myself that another dose is due. I try to take it every 6 hours. (Much better than every 12.) I have lost nearly 12 pounds since Christmas with out dieting and it has helped quite a bit with intense sleep problems. If I can't sleep well, I will take 1/2 an antihistamine tablet (chlortrimeton) and sleep like a baby. I am at the maximum dose of 600mg per day. I wonder if it wouldn't work better with a mood stabilizer, but the Doc won't give me the chance to try and find out. I know tricyclics and SSRI's worked much better than Serzone does but I had gained 60 pounds over the last 15 or so years so the Doctor wanted to see if Serzone would normalize my appetite and metabalism. So far, it IS working. My appetite has really decreased. I certainly wish it was a more effective antidepressant, but it helps some in that regard. Good Luck, Aylese


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