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MAOI characteristics

Posted by Karen on December 17, 1999, at 3:10:30

In reply to To DC: Re: MAOI characteristics, posted by Mark on December 16, 1999, at 0:20:14

> D.C.- What dosage were you on the Nardil? Did it cause any side effects, especially weight gain, and how closely did you follow the dietary restrictions? Also, how did it make you feel in social situations- were you overly sedated and "stoned" like on the benzos or were you confident and wide-awake like the SSRIs? Finally, how long did it take to work?
> > I think that's a good question about MAOI personalities. I have taken Nardil, Parnate, and Selegeline. Nardil works very well for social phobia. One of the weird things about this drug is that it relaxes and stimulates you at the same time. When I took it I felt very relaxed around people but also was wide awake and could stay up all night without getting tired. In some people Nardil can cause hypomania.
> >
> > Parnate was too stimulating for me; it actually increased my social anxiety. I think this drug works better for depression than anxiety. Some say it has fewer side effects than Nardil.
> >
> > Selegeline is used primarily for Alzheimer's disease. It targets the dopamine system and has far fewer side effects. I tried it for a couple of weeks with no noticeable result.

How much do the MAOIs differ in effectiveness-if someone has had an adequate trial of Nardil with no benefit is there any point in trying Parnate or Marplan?




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