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Re: Lofepramine and tricyclics

Posted by Elizabeth on November 3, 1999, at 12:05:09

In reply to Re: Lofepramine and tricyclics, posted by Refractory on November 1, 1999, at 21:24:13

> Hmmmm that is very interesting. I always heard MAOIs were the drugs for the "atypical" form of depression. How come you say SSRIs are good for atypical depression? Very interesting.

This was observed pretty early on, I think. My suspicion is that they still don't work as well for atypical depression as MAOIs, though this hasn't been shown.

See, for example:

Pande AC, et al. Fluoxetine versus phenelzine in atypical depression. Biol Psychiatry. 1996 Nov 15;40(10):1017-20.




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