Posted by Nancy on April 10, 1999, at 18:15:46
In reply to Re: Dysthymia/Bipolar Depression (Elaine), posted by Nick on April 10, 1999, at 13:37:54
However, Respiradone and Zyprexa didn't work for me (a severely bipolar 1, rapid cycler and treatment resistive). Recent augmentation of my treatments with T3 and T4 (to get the thyroid function into the upper-quartile range of "normal") have miraculously improved physiological responsiveness to AD and mood stabilizing meds.
> > I have been dx'd bipolar (NOS) but also have dysthymia. Do you know if this type of medication is supposed to be effective for depression in bipolars, particularly acute depressions?
>
> I don't know of anything yet BUT both risperidone and olanzapine have mood lifting properties and can also be useful for the treatment of mania/hypomania. However, they have a different mechanism of action to amisulpride (D2, D3 blocker, although potentiates DA transmission at low dose) Risperidone MAY be undergoing trials in bipolar disorder as a single therapeutic agent. I would have thought that amisulpiride might be a reasonable experiment, although at low dose with potentiation of DA transmission there is a risk (theoretically) of precipitating mania.
poster:Nancy
thread:4588
URL: http://www.dr-bob.org/babble/19990501/msgs/4675.html