Posted by nick on April 9, 1999, at 7:37:32
In reply to Dysthymia/Treatment Resistant Depressions, posted by JohnB. on April 8, 1999, at 23:24:43
> Amisulpiride has been used in France for the treatment of dysthymis for sometime. Flupenthixol is licensed for 'mild depression' in the UK. Venlafaxine at high dosage has some DA reuptake blockade, and paroxetine also has some pro-dopaminergic action. The Hospital trials in the 1960s sugest chlorpromazine to be superior to placebo as an antidepressant.
Clinical experience suggests however that neuroleptics are not as potent an antidepressant as more usual drugs, and that they can cause profound dysphoria (David Healy's work - not sure if it's been published yet.) Still, interesting developments.
Nick
poster:nick
thread:4588
URL: http://www.dr-bob.org/babble/19990501/msgs/4606.html