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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 22 of 22. This is the beginning of the thread.
Posted by joe f on July 19, 2018, at 21:02:10
why has rexulti proven to be a financial failure for its manufacturer..is it cost or efficacy?
Posted by Lamdage22 on July 19, 2018, at 23:32:02
In reply to REXULTI A FINANCIAL FAILURE, posted by joe f on July 19, 2018, at 21:02:10
Does that mean it wont be produced anymore?
Posted by joe f on July 20, 2018, at 5:57:15
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by Lamdage22 on July 19, 2018, at 23:32:02
No it will be produced but its manufacturer thought it to be its next blockbuster as per its abilify......and sales are dismal.....have you tried it?
Posted by linkadge on July 20, 2018, at 11:44:09
In reply to REXULTI A FINANCIAL FAILURE, posted by joe f on July 19, 2018, at 21:02:10
Just a guess,
Perhaps it doesn't offer enough of an advantage over abilify to justify people switching to a brand name drug vs. a generic?
Linkadge
Posted by Christ_empowered on July 20, 2018, at 18:22:22
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by linkadge on July 20, 2018, at 11:44:09
i forget the exact %, but something like 2/3 of ongoing tranquilizer prescriptions go thru Medicaid or Medicare. with abilify now generic, maybe the gov't is putting pressure on prescribers to avoid rexulti and that other one...the v-one...
i dunno. other than that...its -very- new and just reading about it as a person/patient who needs a tranq, daily...it doesn't seem so great. narrow dosage range, very expensive, potential prolactin elevation, plus all the akathisia and EPS from abilify, anyway. why bother?
Posted by joe f on July 20, 2018, at 18:41:40
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by Christ_empowered on July 20, 2018, at 18:22:22
well I,ve been on it 3 months at 2mg doesn't seem to make a difference ...eliminating the klonopin has gotten me out of my hole
Posted by Christ_empowered on July 20, 2018, at 20:24:33
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by joe f on July 20, 2018, at 18:41:40
yeah...Mother's Little Helpers can dampen mood,especially Klonopin. It wasn't until I'd been off the Klonopin for...12 months, maybe longer...that my so-called "severe depression" let up. turns out...
AM agitation? yeah, that's interdose anxiety. Slowed thoughts? 3mgs/Klonopin for a teenager will do that.
The other benzodiazepines can cause problems, but I don't think its in the same league as clonazepam. dosage is also an issue. 40mgs/valium might not be a problem, but ramp it up to 60mgs (or equivalent in something else...), and you might hit a low point.
xanax was (is?) used, now and then, in some forms of depression. there's an xr now, which I haven't taken and don't know much about...maybe its easier to taper?
hope things get better for you. im glad you've switched out the klonopin for something less noxious.
Posted by joe f on July 20, 2018, at 21:31:54
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by Christ_empowered on July 20, 2018, at 20:24:33
on 15ng valium to sleep and 2mg in am and 2mg in pm...so total about 20 daily........last dose of klonopin was 2 weeks sgo
Posted by Lamdage22 on July 21, 2018, at 0:33:16
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by joe f on July 20, 2018, at 5:57:15
have you tried it?
No but i will approach my doctor about it in two weeks.
Posted by Jeroen on July 21, 2018, at 11:00:28
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by Lamdage22 on July 21, 2018, at 0:33:16
more manic gamblers from REXULTI = FAIL
Posted by Lamdage22 on July 21, 2018, at 13:23:48
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by Jeroen on July 21, 2018, at 11:00:28
Haha.
Posted by joe f on July 21, 2018, at 17:40:18
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by Lamdage22 on July 21, 2018, at 0:33:16
approach what lamdadge..thanks
Posted by Lamdage22 on July 22, 2018, at 2:42:47
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by joe f on July 21, 2018, at 17:40:18
I will approach my doctor about Rexulti.
> approach what lamdadge..thanks
Posted by joe f on July 22, 2018, at 8:10:43
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by Lamdage22 on July 22, 2018, at 2:42:47
so you are thinking maybe its a waste of my time with no benefits?
Posted by Lamdage22 on July 22, 2018, at 9:08:58
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by joe f on July 22, 2018, at 8:10:43
I dont think there is a drug in the world that will make me gamble. Im just not keen to lose money. Im not sure why you are asking that. Do you think Rexulti is bad compared to Abilify?
> so you are thinking maybe its a waste of my time with no benefits?
Posted by Jeroen on July 22, 2018, at 9:42:24
In reply to Re: REXULTI A FINANCIAL FAILURE, posted by Lamdage22 on July 22, 2018, at 9:08:58
its on their website friend
if you experience gambling contact your doctor lol
Posted by Lamdage22 on July 22, 2018, at 10:37:30
In reply to Re: Abilify and gambling, posted by Jeroen on July 22, 2018, at 9:42:24
So i just pop a Rexulti before and when i lose i will sue Lundbeck?
Posted by Christ_empowered on July 22, 2018, at 11:32:12
In reply to Re: Abilify and gambling, posted by Lamdage22 on July 22, 2018, at 10:37:30
hi. sometimes, tranquilizers in general can cause or exacerbate ocd-type problems. its not just abilify. especially as the dose goes up, the 'atypicals' can cause a mix of reduced frontal lobe activity and increased obsessive stuff. ive seen case reports for both zyprexa and clozapine.
with abilify...i think 1 reason they're dealing with legal stuff is because abilify can also be somewhat stimulating, so instead of having increased ocd problems and heavy sedation, there's increased ocd stuff and a bit of activation.
the other problem, which i think is a big problem with abilify, is that its been sprayed on people who probably don't need neuroleptics. if one deals with psychosis, mania, etc., then a neuroleptic makes sense. with widespread prescribing, a lot of people with more moderate problems are experiencing serious adverse effects, and they're running to the nearest law firm (its America, LOL).
Posted by joe f on July 22, 2018, at 17:51:52
In reply to Re: Abilify and gambling, posted by Christ_empowered on July 22, 2018, at 11:32:12
since I am now 2 weeks off of klonopin and on the valium and the dr added a low dose of adderal 5mg 2x daily feel great...I wonder why i'm even on rexulti
Posted by Christ_empowered on July 22, 2018, at 19:19:30
In reply to Re: Abilify and gambling, posted by joe f on July 22, 2018, at 17:51:52
i think low dose adderall and various doses of ritalin can be helpful for a lot people w/o the problems one sees with antidepressants. i dont know much about provigil or nuvigil, but some people swear by the stuff.
if you can taper off tranquilizers/antipsychotics, id say do it. they carry very serious risks, after all...and new(er) ones are very expensive.
some people do well on a neuroleptic+stimulant. its an old school remedy, there used to be combo pills with antipsychotics and uppers in one capsule. the "goof balls" are no longer around in 1 convenient pill, but the same sorts of drugs are combined to get symptom control for some people.
my only real advice would be to be very slow and cautious about tapering anything, especially benzodiazepines and the antipsychotics. with the neuroleptics...the new ones cover a lot of territory in the brain, so its a good idea to go slowly, give your brain and whole body some time to reset.
hope this helps.
Posted by joe f on July 22, 2018, at 21:29:54
In reply to Re: Abilify and gambling, posted by Christ_empowered on July 22, 2018, at 19:19:30
yes you are right I take 20 valium ...15mg to sleep 200 luvox 10 addellal and 2 rexulti...and feeling pretty decent maybe will ask to taper rexulti slowly as I never thought it did much ..my improvement came with the adderrall and valium and getting rid of klonopin
Posted by Clearskies on July 24, 2018, at 19:41:08
In reply to REXULTI A FINANCIAL FAILURE, posted by joe f on July 19, 2018, at 21:02:10
> why has rexulti proven to be a financial failure for its manufacturer..is it cost or efficacy?
Its a financial failure for me personally! It is working better, cleaner than Abilify did, but its not covered by Medicare, and none of the manufacturers discount cards apply if youre on a government program. Im surviving on samples and will until my doctor runs out of them or she finds a way for it to be a reasonable price. $254 for a 30 day supply is enough to make my depression...worse.
This is the end of the thread.
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