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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 14 of 14. This is the beginning of the thread.
Posted by SLS on August 26, 2006, at 6:27:11
Does Lyrica have the potential to treat bipolar depression? What dosages? How long does it take to work?
Thanks.
- Scott
Posted by willyee on August 26, 2006, at 16:19:45
In reply to Lyrica (pregabalin) for bipolar depression?, posted by SLS on August 26, 2006, at 6:27:11
> Does Lyrica have the potential to treat bipolar depression? What dosages? How long does it take to work?
>
> Thanks.
>
>
> - ScottIf its anything like Nuerontinon,then it`s best use is gonna be in vivo with a benzo,either dosed together,or apart,just built up along with one over a few days.
Alone this chemical is a tricky one,it mimics euphoria at first,the kind of being drunk,and while some dont like that,most suffferers dont mind a buzz,however this dies and there is a notable depressing effect brought on by it,and it is really most appearent only when you stop it,and you notice you feel better.
Taking it in low doses along a benzo,i feel gives a added mood stablization that a benzo seems to lack,it serves to make a benzo more solid,and i dont mean anxiety,i mean anger,depression,and mixed states,over all mood,it just varies on how much of it you use to the degree your mood swings,but again its purpose seems to be working behind the scenes more and adding more benifit to a benzo so its more than just an anxiety qwelling drug.
I know my doc refused to give me lyrcia as she said the chemical profile difference of it and Nuerontion were so small,and i was already on Nuerontion,that she dident feel the risk of adding a new drug such as it to my cocktail when i was in a way already using it,although i wanted to try the new drug,i did think what she was saying made sense,i was covered on this one,i wasnt having issues using the high dose such as pyhsical side effects,so nothing really opted to go to lyrcia other than curisoity.
I will tell you this,be cautious using it monotherapy,we still have our local ambulance chases flashing neurontinon commercials here all the time trying to get sucideal ideation suits in.I actualy agree,its a drug to be used in moderation as it can worsen depression if not used correctly,but i am sure you can work that part out,its more of a listen to your body type of thing.
Posted by SLS on August 27, 2006, at 11:25:11
In reply to Re: Lyrica (pregabalin) for bipolar depression?, posted by willyee on August 26, 2006, at 16:19:45
> I actualy agree,its a drug to be used in moderation as it can worsen depression if not used correctly,
It is interesting that several people have reported some antidepressant activity for this drug. I don't know if it has been consistent for them, though.
Thanks for your input.
- Scott
Posted by willyee on August 27, 2006, at 12:37:08
In reply to Re: Lyrica (pregabalin) for bipolar depression?, posted by SLS on August 27, 2006, at 11:25:11
> > I actualy agree,its a drug to be used in moderation as it can worsen depression if not used correctly,
>
> It is interesting that several people have reported some antidepressant activity for this drug. I don't know if it has been consistent for them, though.
>
> Thanks for your input.
>
>
> - ScottWell i cant attest there certainly is at first,not only is there a NEW kind of anxiety relief not felt before from a benzo,you also have a mild but safe feeling buzz.
However the buzz is the first to stop,and you soon begin not even to notice you are taking it,the anxiety relieaf usualy stays but thats when for me anyway the depression slowly sets in,but again this is with Nuerontinon and myself.In fact i knew a lot of GHB users who thought they found a legal safer alternative when the buzz factor was noticed at the onset of the drugs introduction,this is why in my view its important not to get caught up in this because that buzz usualy means your on a high dose,a more effective dose that will not cause depression but instead balance mood will be one hardly noticed alone.
Lyrcia might be different,but id really find it hard to use it monothreapy,perhaps a stimulant used ,i know you mentioned emsam,might work well,let us know.
Good luck.
Posted by MARTY on August 27, 2006, at 15:08:24
In reply to Re: Lyrica (pregabalin) for bipolar depression?, posted by willyee on August 26, 2006, at 16:19:45
Hi Willyee,While Pregabalin is an analog (derivative?) of Gabapentin, it feels very differently to the point it's a shame it's linked with Gabapentin.
Very underused in my opinion.
Hope you do well,
Marty> > Does Lyrica have the potential to treat bipolar depression? What dosages? How long does it take to work?
> >
> > Thanks.
> >
> >
> > - Scott
>
> If its anything like Nuerontinon,then it`s best use is gonna be in vivo with a benzo,either dosed together,or apart,just built up along with one over a few days.
>
> Alone this chemical is a tricky one,it mimics euphoria at first,the kind of being drunk,and while some dont like that,most suffferers dont mind a buzz,however this dies and there is a notable depressing effect brought on by it,and it is really most appearent only when you stop it,and you notice you feel better.
>
>
> Taking it in low doses along a benzo,i feel gives a added mood stablization that a benzo seems to lack,it serves to make a benzo more solid,and i dont mean anxiety,i mean anger,depression,and mixed states,over all mood,it just varies on how much of it you use to the degree your mood swings,but again its purpose seems to be working behind the scenes more and adding more benifit to a benzo so its more than just an anxiety qwelling drug.
>
>
> I know my doc refused to give me lyrcia as she said the chemical profile difference of it and Nuerontion were so small,and i was already on Nuerontion,that she dident feel the risk of adding a new drug such as it to my cocktail when i was in a way already using it,although i wanted to try the new drug,i did think what she was saying made sense,i was covered on this one,i wasnt having issues using the high dose such as pyhsical side effects,so nothing really opted to go to lyrcia other than curisoity.
>
>
> I will tell you this,be cautious using it monotherapy,we still have our local ambulance chases flashing neurontinon commercials here all the time trying to get sucideal ideation suits in.
>
> I actualy agree,its a drug to be used in moderation as it can worsen depression if not used correctly,but i am sure you can work that part out,its more of a listen to your body type of thing.
Posted by ed_uk on August 27, 2006, at 15:08:30
In reply to Lyrica (pregabalin) for bipolar depression?, posted by SLS on August 26, 2006, at 6:27:11
Hi Scott
I expect you might find Lyrica similar to Neurontin, but maybe stronger in its effects.
Ed
Posted by MARTY on August 27, 2006, at 15:15:47
In reply to Lyrica (pregabalin) for bipolar depression?, posted by SLS on August 26, 2006, at 6:27:11
Hi Scott,I've tried both Neurontin and Lyrica and can tell you it isn't feeling the same. Their is at first something people describes as 'drunk feeling' but while it's described with the same words, it doesn't feel the same.
Low dose Lyrica induce sleepiness while high dose (300mg(600mg?) to 1200mg) is stimulating.
For me, as for some other (ask Crazy Horse), it's even better for anxiety than most benzos (xanax, Klonopin included) ...
As for the antidepressant feeling, as of now it's definitively there.
It's interesting to note that we're both having the same diagnostic (Bipolar Type 4)
btw, do you have social phobia ? if so, is it episodic ?
Marty
> Does Lyrica have the potential to treat bipolar depression? What dosages? How long does it take to work?
>
> Thanks.
>
>
> - Scott
Posted by Phillipa on August 27, 2006, at 16:17:25
In reply to Re: Lyrica (pregabalin) for bipolar depression? » SLS, posted by MARTY on August 27, 2006, at 15:15:47
Hi Marty long time. Yup Crazy Hourse loves his lyrica. Love Phillipa
Posted by Phillipa on August 27, 2006, at 16:18:46
In reply to Re: Lyrica (pregabalin) for bipolar depression? » MARTY, posted by Phillipa on August 27, 2006, at 16:17:25
Oh Jakeman was taking it too. He switched to another med. But he's not bipolar. Love Phillipa
Posted by SLS on August 27, 2006, at 19:02:27
In reply to Re: Lyrica (pregabalin) for bipolar depression? » SLS, posted by MARTY on August 27, 2006, at 15:15:47
> It's interesting to note that we're both having the same diagnostic (Bipolar Type 4)
>
> btw, do you have social phobia ? if so, is it episodic ?Yes, social anxiety has been a part of my condition, particularly when I was younger. I have learned to manage it, though. Some homemade CBT and desensitization have been helpful.
What dosage of Lyrica are you taking?
- Scott
Posted by willyee on August 27, 2006, at 22:23:36
In reply to Re: Lyrica (pregabalin) for bipolar depression? » willyee, posted by MARTY on August 27, 2006, at 15:08:24
>
> Hi Willyee,
>
> While Pregabalin is an analog (derivative?) of Gabapentin, it feels very differently to the point it's a shame it's linked with Gabapentin.
>
> Very underused in my opinion.
>
> Hope you do well,
> Marty
>
Thats odd,i think your the first person i remember making this statement,usualy the response i got was they are the same to a degree,and that lyrcia had a benifit of allowing you to take a much lower dose to achieve the same benifits you would off Nuerontinin.This was when i was considering lyrcia,but after my doc who mind you at first dident acnowledge it was out there,second dident know anything on it,read who knows what,then on my next visit after promising to look into it came back with her response that she would NOT consider it an option since i had already raised nuerontinin so high.
Shes been fairly reasonable so far with my complex and probuably hair pulling requests,so i guess i can let her slide on this one issue,but i dont think it would be an option for me.Its a shame i feel grateful to have a doc who simply gives me a maoi here and tolerate service im not happy with,but im just that scared of being hung out to dry,as i saw the coldness these people are capable of when due to no ones fault i ran out of klonopin,i posted my story,everyone in the industry turned there back to me when i and my insurance shelled out all this money to them,and all i wanted were a few lousy klonopin tablets to my doc appt,i was given the ice shoulder,no one cared,no one was fearful i was out of this critical med,so im literaly at a docs wimb with my maoi.Luckly i found a combo now involving two mood stablizers combined in low dose,and im either getting some fair benifit from this or im in a semi remission state,either way im using it as i always do to get some options back in my bag,as we all know a remission state,no matter how strong it is,mine being pretty weak,are unpredictable,i learned my lesson about going and running out and making all types of plans,i lost a lot of friends because of that,so instead,im getting things in order,and focusing on getting some game plans back as they are running way too thin for my liking,way to thin.
Just fyi,part of the combo if it is the combo that is helping,is the use of both depakote and Nuerontinin in very small doses,half of half a stand alone dose.
Anyway sorry for the long post,but going back to square one,again ive heard few people say there was a major difference in Nuerontins effect and lyrcia`s.......this is not to downplay yours,i hoped there was a differance.
> > > Does Lyrica have the potential to treat bipolar depression? What dosages? How long does it take to work?
> > >
> > > Thanks.
> > >
> > >
> > > - Scott
> >
> > If its anything like Nuerontinon,then it`s best use is gonna be in vivo with a benzo,either dosed together,or apart,just built up along with one over a few days.
> >
> > Alone this chemical is a tricky one,it mimics euphoria at first,the kind of being drunk,and while some dont like that,most suffferers dont mind a buzz,however this dies and there is a notable depressing effect brought on by it,and it is really most appearent only when you stop it,and you notice you feel better.
> >
> >
> > Taking it in low doses along a benzo,i feel gives a added mood stablization that a benzo seems to lack,it serves to make a benzo more solid,and i dont mean anxiety,i mean anger,depression,and mixed states,over all mood,it just varies on how much of it you use to the degree your mood swings,but again its purpose seems to be working behind the scenes more and adding more benifit to a benzo so its more than just an anxiety qwelling drug.
> >
> >
> > I know my doc refused to give me lyrcia as she said the chemical profile difference of it and Nuerontion were so small,and i was already on Nuerontion,that she dident feel the risk of adding a new drug such as it to my cocktail when i was in a way already using it,although i wanted to try the new drug,i did think what she was saying made sense,i was covered on this one,i wasnt having issues using the high dose such as pyhsical side effects,so nothing really opted to go to lyrcia other than curisoity.
> >
> >
> > I will tell you this,be cautious using it monotherapy,we still have our local ambulance chases flashing neurontinon commercials here all the time trying to get sucideal ideation suits in.
> >
> > I actualy agree,its a drug to be used in moderation as it can worsen depression if not used correctly,but i am sure you can work that part out,its more of a listen to your body type of thing.
>
>
Posted by MARTY on August 28, 2006, at 1:54:13
In reply to Re: Lyrica (pregabalin) for bipolar depression? » MARTY, posted by SLS on August 27, 2006, at 19:02:27
CBT helped me too. With the consent of my pdoc, I'm currently trying different dosage\pattern. Right now my best one is 300mg before bed and 150mg at noon.
Marty
> > It's interesting to note that we're both having the same diagnostic (Bipolar Type 4)
> >
> > btw, do you have social phobia ? if so, is it episodic ?
>
> Yes, social anxiety has been a part of my condition, particularly when I was younger. I have learned to manage it, though. Some homemade CBT and desensitization have been helpful.
>
> What dosage of Lyrica are you taking?
>
>
> - Scott
Posted by SLS on August 28, 2006, at 7:42:03
In reply to Re: Lyrica (pregabalin) for bipolar depression? » SLS, posted by MARTY on August 28, 2006, at 1:54:13
> With the consent of my pdoc, I'm currently trying different dosage\pattern. Right now my best one is 300mg before bed and 150mg at noon.
What dosage did you start at?
- Scott
Posted by MARTY on August 28, 2006, at 11:33:59
In reply to Re: Lyrica (pregabalin) for bipolar depression? » MARTY, posted by SLS on August 28, 2006, at 7:42:03
Well, I tried it at 900mg for 2 days... was almost hallucinating because because I didn't titrate (it feel like GHB and exctasy). But I known that it would do that, I did it on purpose because I didn't think it was a med for me or that it would do anything good at high dose (I already had tried it at 50mg, 75mg.. hated it)Then I tried 600mg for 2 days; thought it was too much so I'm now on 300mg since.
But today I will try it back at 600mg but 300mg BID style, not 600mg one shot.
Btw, how did you felt on Neurontin ? I wasn't doing much for me.
Marty
Psymeds abuser ;)
> > With the consent of my pdoc, I'm currently trying different dosage\pattern. Right now my best one is 300mg before bed and 150mg at noon.
>
> What dosage did you start at?
>
>
> - Scott
This is the end of the thread.
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