Psycho-Babble Medication Thread 606264

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What diffrence is the [I] isomer in amphetamine

Posted by rjlockhart on February 4, 2006, at 11:56:29

Adderall consisist of 25% I isomer of and 75 % of D isomer.

I have read the d-isomer is the more activating, mentally, but the I is more stimulating on the body. Is this true?

And does the I have any effect on the brain.

I rerember when i took Adderall that my speech was increased rapidly, and Dexedrine it is not, im not as "zinged"

Anyone?

 

Re: What diffrence is the [I] isomer in amphetamine

Posted by mike99 on February 4, 2006, at 12:18:42

In reply to What diffrence is the [I] isomer in amphetamine, posted by rjlockhart on February 4, 2006, at 11:56:29


Amphetamine is either in the form of an L or D isomer (levoamphetamine or dextroamphetamine).

You're correct that the D isomer is more active in the brain whereas the L isomer has minimal effects on the brain compared to its peripheral actions on the body (heart rate, blood pressure).

It may be a matter of debate, but I don't think the L-isomer is of much if any benefit in terms of stimulating the brain (ie having any clinical benefits-- it is active in the brain to a small degree).

 

Re: What diffrence is the [I] isomer in amphetamine

Posted by PsychoPharmaFiender on February 4, 2006, at 12:52:56

In reply to Re: What diffrence is the [I] isomer in amphetamine, posted by mike99 on February 4, 2006, at 12:18:42

What may not seem like alot on paper sometimes does not translate that way in terms of clinical effects on people. Lots of people respond better to adderall than Dexedrine, the only difference is that Adderall contains DL amphetamine, where as Dexedrine is D amphetamine.

Same thing for Celexa and Lexapro.

> Amphetamine is either in the form of an L or D isomer (levoamphetamine or dextroamphetamine).
>
> You're correct that the D isomer is more active in the brain whereas the L isomer has minimal effects on the brain compared to its peripheral actions on the body (heart rate, blood pressure).
>
> It may be a matter of debate, but I don't think the L-isomer is of much if any benefit in terms of stimulating the brain (ie having any clinical benefits-- it is active in the brain to a small degree).
>
>

 

Re: What diffrence is the [I] isomer in amphetamine » PsychoPharmaFiender

Posted by mike99 on February 4, 2006, at 13:42:23

In reply to Re: What diffrence is the [I] isomer in amphetamine, posted by PsychoPharmaFiender on February 4, 2006, at 12:52:56


Yeah, I'm probably being too theoretical. Many do seem to do better on Adderall than Dex (and vice versa).

> What may not seem like alot on paper sometimes does not translate that way in terms of clinical effects on people. Lots of people respond better to adderall than Dexedrine, the only difference is that Adderall contains DL amphetamine, where as Dexedrine is D amphetamine.
>
> Same thing for Celexa and Lexapro.
>
> > Amphetamine is either in the form of an L or D isomer (levoamphetamine or dextroamphetamine).
> >
> > You're correct that the D isomer is more active in the brain whereas the L isomer has minimal effects on the brain compared to its peripheral actions on the body (heart rate, blood pressure).
> >
> > It may be a matter of debate, but I don't think the L-isomer is of much if any benefit in terms of stimulating the brain (ie having any clinical benefits-- it is active in the brain to a small degree).
> >
> >
>
>

 

Re: What diffrence is the [I] isomer in amphetamine

Posted by Phillipa on February 4, 2006, at 20:52:13

In reply to Re: What diffrence is the [I] isomer in amphetamine » PsychoPharmaFiender, posted by mike99 on February 4, 2006, at 13:42:23

Matt are you taking psychopharmacology? Maybe stock broker isn't your bag have you considered getting into medicine? Fondly, Phillipa

 

Re: What diffrence is the [I] isomer in amphetamine

Posted by rjlockhart on February 6, 2006, at 13:16:07

In reply to Re: What diffrence is the [I] isomer in amphetamine, posted by Phillipa on February 4, 2006, at 20:52:13

Phillpa thats confidecial. Rerember.

Matt

 

Re: What diffrence is the [I] isomer in amphetamine » Phillipa

Posted by Phillipa on February 6, 2006, at 18:52:56

In reply to Re: What diffrence is the [I] isomer in amphetamine, posted by Phillipa on February 4, 2006, at 20:52:13

Matt which is confidential? Babblemail me okay? Love Mom Phillipa


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