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Re: What diffrence is the [I] isomer in amphetamine

Posted by mike99 on February 4, 2006, at 12:18:42

In reply to What diffrence is the [I] isomer in amphetamine, posted by rjlockhart on February 4, 2006, at 11:56:29


Amphetamine is either in the form of an L or D isomer (levoamphetamine or dextroamphetamine).

You're correct that the D isomer is more active in the brain whereas the L isomer has minimal effects on the brain compared to its peripheral actions on the body (heart rate, blood pressure).

It may be a matter of debate, but I don't think the L-isomer is of much if any benefit in terms of stimulating the brain (ie having any clinical benefits-- it is active in the brain to a small degree).


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URL: http://www.dr-bob.org/babble/20060129/msgs/606274.html