Psycho-Babble Medication Thread 466086

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Wellbutrin's effect on brain chemicals??

Posted by MM on March 3, 2005, at 17:07:01

Anyone know what Wellbutrin's exact effect on Dopamine and Norepinephrine is? I read an article that said increasing Norepinephrine is not a good idea for people with anxiety, meaning it increases it (or at least for people with Panic attacks), so I'm wondering if that's why Wellbutrin causes anxiety? Smoking increases Dopamine which is probably why so many anxious people smoke (or am I wrong about the Dopamine?) and why Wellbutrin is good for quitting smoking.

 

Re: Wellbutrin's effect on brain chemicals??

Posted by Spriggy on March 3, 2005, at 18:05:18

In reply to Wellbutrin's effect on brain chemicals??, posted by MM on March 3, 2005, at 17:07:01

I have anxiety and panic attacks and Wellbutrin sent me straight into panic mode for days and days.

I couldn't sleep, couldn't eat and felt like I was a time bomb waiting to explode.


Now.. when I've drank a ton of coffee (which hits dopamine), I do just fine. So I'm wondering if it was the Norepiphrine that whacked me out a bit too.

 

Re: Wellbutrin's effect on brain chemicals?? » Spriggy

Posted by MM on March 3, 2005, at 18:27:45

In reply to Re: Wellbutrin's effect on brain chemicals??, posted by Spriggy on March 3, 2005, at 18:05:18

When I was on Serzone, which I believe hits serotonin and norepinephrine, it was this double thing where I felt panicky and anxious yet I also felt kind of like *meh, eff it* at the same time (so I had more energy than a straight SSRI, but it was the bad kind and I was still apathetic). Now I have this double thing on Wellbutrin where I can pull myself out of the depression but I think it's causing me to be anxious at the same time (I've noticed this more now that I went up from 75 to 150). It's weird because I've also heard that Norepinephrine is good for anxiety, so I dunno (why I asked I guess).
Maybe I'll try getting off the Wellbutrin and just drink 50 cups of coffee a day :D.
Thanks for the reply, Spriggy.
MM

 

Re: Wellbutrin's effect on brain chemicals??

Posted by empty inside on March 5, 2005, at 1:32:06

In reply to Re: Wellbutrin's effect on brain chemicals?? » Spriggy, posted by MM on March 3, 2005, at 18:27:45

I have no clue about the science... but I do know that my hands shake tremendously on Wellbutrin (I think it's XL? Not sure if there is a difference between reg and XL anyway?)... I am on a high dose though. 600mg and i'm well under 100 pounds. I feel jittery for a period of a few hours during the day when I take it. Nothing at all like the anxiousness I experienced on Adderall, however. I find it helps me focus and keeps me on task. The only thing I mind is the hands shaking. I used to consider myself an artist. I would like to think so anyway. But I can't produce anything but garbage without a steady hand :( My favorite thing to do was stipling pen & ink -- millions of tiny dots -- so obviously that's out of the question now.

 

Re: Wellbutrin's effect on brain chemicals?? » empty inside

Posted by MM on March 5, 2005, at 1:35:26

In reply to Re: Wellbutrin's effect on brain chemicals??, posted by empty inside on March 5, 2005, at 1:32:06

That seems like a really high dose to me, but err what do I know? Have you tried a smaller dose? I've noticed if I get really upset, crying etc., my hands get a little trembly on it....Maybe a beta-blocker would help?


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