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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by meejet on April 19, 2004, at 11:43:19
I have been diagnosed with clinical depression and have spent the past 10 years on each SSRI with limited effectivity. I am now on Effexor which activates both the seratonin and norepinephrine reuptake inhibitors. I am thinking that I wish to increase the supply of seratonin to my brain as well as limit the reuptake of it. I called Wyeth (manufacturer of Effexor) to ask about combination therapy using 5-HTP and they have no research on the subject; however they cautioned me on "Seratonin Syndrome" which can be fatal. Is there anyone who has attempted both 5-HTP and an SSRI or Effexor who has practical advice on the results or symptoms to watch to avoid "Seratonin Syndrome"?
Posted by almondjoy on April 20, 2004, at 15:25:48
In reply to Drug interactions: 5-HTP and Effexor, posted by meejet on April 19, 2004, at 11:43:19
"Seratonin Syndrome" which can be fatal. Is there anyone who has attempted both 5-HTP and an SSRI or Effexor who has practical advice on the results or symptoms to watch to avoid "Seratonin Syndrome"?
>here's a personal experience
http://leda.lycaeum.org/?ID=6583
http://www.erowid.org/experiences/exp.php?ID=12878and this page on effexor warns against taking with tryptophan (i think 5-htp makes tryptophan in your body) bcos it will cause serotonin syndrome
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202764.htmlSymptoms: euphoria, drowsiness, sustained rapid eye movement, overreaction of the reflexes, rapid muscle contraction and relaxation in the ankle causing abnormal movements of the foot, clumsiness, restlessness, feeling drunk and dizzy, muscle contraction and relaxation in the jaw, sweating, intoxication, muscle twitching, rigidity, high body temperature, mental status changes were frequent (including confusion and hypomania - a "happy drunk" state), shivering, diarrhea, loss of consciousness and death.
Source: American Journal of Psychiatry, June 1991 "The Serotonin Syndrome"d
d
Posted by Dr. Bob on April 22, 2004, at 0:05:07
In reply to Drug interactions: 5-HTP and Effexor, posted by meejet on April 19, 2004, at 11:43:19
> I am thinking that I wish to increase the supply of seratonin to my brain as well as limit the reuptake of it. I called Wyeth (manufacturer of Effexor) to ask about combination therapy using 5-HTP...
Sorry to interrupt, but I'd like to redirect this thead to Psycho-Babble Alternative. Here's a link:
http://www.dr-bob.org/babble/alter/20040418/msgs/338625.html
Thanks,
Bob
This is the end of the thread.
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