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Re: Drug interactions: 5-HTP and Effexor

Posted by almondjoy on April 20, 2004, at 15:25:48

In reply to Drug interactions: 5-HTP and Effexor, posted by meejet on April 19, 2004, at 11:43:19

"Seratonin Syndrome" which can be fatal. Is there anyone who has attempted both 5-HTP and an SSRI or Effexor who has practical advice on the results or symptoms to watch to avoid "Seratonin Syndrome"?

here's a personal experience

and this page on effexor warns against taking with tryptophan (i think 5-htp makes tryptophan in your body) bcos it will cause serotonin syndrome

Symptoms: euphoria, drowsiness, sustained rapid eye movement, overreaction of the reflexes, rapid muscle contraction and relaxation in the ankle causing abnormal movements of the foot, clumsiness, restlessness, feeling drunk and dizzy, muscle contraction and relaxation in the jaw, sweating, intoxication, muscle twitching, rigidity, high body temperature, mental status changes were frequent (including confusion and hypomania - a "happy drunk" state), shivering, diarrhea, loss of consciousness and death.
Source: American Journal of Psychiatry, June 1991 "The Serotonin Syndrome"






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