Psycho-Babble Medication Thread 335660

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Topomax + weight loss - Any success stories?

Posted by Lainy on April 12, 2004, at 17:35:42

Has anyone experienced weight loss with Topomax? My docter gave it to me for this, but I haven't noticed a change. I'm takeing 50mg x 3 daily.

 

Re: Topomax + weight loss - Any success stories?

Posted by gradstudent on April 14, 2004, at 17:46:07

In reply to Topomax + weight loss - Any success stories?, posted by Lainy on April 12, 2004, at 17:35:42

I just got a script for it today, but will be taking 25mg twice daily (morning and eve). what did your doc say the weight loss would be due to? appetite control or something else? also, what are the side effects you are experiencing? cognitive slowness is a big fear of mine...

 

Re: Topomax + weight loss - Any success stories? » gradstudent

Posted by chemist on April 14, 2004, at 23:58:29

In reply to Re: Topomax + weight loss - Any success stories?, posted by gradstudent on April 14, 2004, at 17:46:07

chemist here....i was doing 100 mg bid and let me tell you there was a weight loss of over 20 lbs. from 168 to about 145. the bad news is that this med is indicated as adjunct therapy to a primary mood stabilizer. you'll get thin and trim but expect cognitive effects (offset in my case by 30 mg dexedrine qd) and all studies indicate that as monotherapy, it's no good. i had better luck with trileptal and dexedrine.....best, chemist

> I just got a script for it today, but will be taking 25mg twice daily (morning and eve). what did your doc say the weight loss would be due to? appetite control or something else? also, what are the side effects you are experiencing? cognitive slowness is a big fear of mine...

 

Re: to chemist

Posted by gradstudent on April 15, 2004, at 3:40:29

In reply to Re: Topomax + weight loss - Any success stories? » gradstudent, posted by chemist on April 14, 2004, at 23:58:29

Scary! I am also on Wellbutrin 450mgs. So you think a dose as low as 50 of Topomax can make me stupid? I guess I'll give it a try. Thanks.

 

Re: to chemist » gradstudent

Posted by chemist on April 16, 2004, at 2:38:13

In reply to Re: to chemist, posted by gradstudent on April 15, 2004, at 3:40:29

> Scary! I am also on Wellbutrin 450mgs. So you think a dose as low as 50 of Topomax can make me stupid? I guess I'll give it a try. Thanks.

it won't make you stupid: topamax is renouned for cognitive impairment. at 50 mg qd, you are in the noise level, so i would think that the cognitive effects would be slim to none. topamax is very well established as a drug that will cause you to lose weight and, in higher doses, make word-finding difficult and shortening you attension span. as long as you have a primary modd stabilizer on board, topamax is indicated for offsetting the weight gain that is usually associated with drugs such as lithium carbonate, depakote, zyprexa, and others of that ilk. there is a significant body of literature that asscociates cognitive impairment with the abovementioned drugs as well; topamax is the highest scorer in that regard. if you have problems, look into a cholinesterase inhibitor, which will not only offest the impairment but might add mood stabilizing effects as well. fyi, this last bit of info comes from dr. steve dubovsky, the man who wrote the book on novel bipolar treatments. hope all is well, and best regards, chemist


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