Psycho-Babble Medication Thread 241313

Shown: posts 1 to 25 of 43. This is the beginning of the thread.

 

zonegran and bipolar II

Posted by River1924 on July 12, 2003, at 20:43:31

I just added the anticonvulsant, zonegran, to the antidepressant, effexor, and the anxiety med, klonipin. I'm amazed at how much better I feel and act. Bipolar II is my new diagnosis: hence my doctor has added a mood stabilizer to medication regimen. Has anyone else tried zonegran for moodiness, moodswings, etc..? Will this 100mg of zonegran continue to work long term?

 

Re: zonegran and bipolar II

Posted by SLS on July 12, 2003, at 23:17:53

In reply to zonegran and bipolar II, posted by River1924 on July 12, 2003, at 20:43:31

> I just added the anticonvulsant, zonegran, to the antidepressant, effexor, and the anxiety med, klonipin. I'm amazed at how much better I feel and act. Bipolar II is my new diagnosis: hence my doctor has added a mood stabilizer to medication regimen. Has anyone else tried zonegran for moodiness, moodswings, etc..? Will this 100mg of zonegran continue to work long term?


Hi.

In what ways does Zonegran make you feel better? Does it have an antidepressant effect?

Thanks.


- Scott

 

zonegran and bipolar II/nausea/fatigue

Posted by River1924 on July 15, 2003, at 18:44:47

In reply to Re: zonegran and bipolar II, posted by SLS on July 12, 2003, at 23:17:53

I began zonegran a week ago. Does it cause nausea? My moods seem confined within a smaller range and I'm more outgoing and, in general, less anxious. Anyone think the nausea (which isn't bad) will go away? I'm having some fatigue, too. Will that decrease?

 

zonegran and bipolar II

Posted by River1924 on July 16, 2003, at 23:19:57

In reply to zonegran and bipolar II/nausea/fatigue, posted by River1924 on July 15, 2003, at 18:44:47

Has anyone out there besides me been on zonegran for reasons besides epilepsy? I feel like I'm alone out here. (Is zonegran owned by a small company or something and only marketed in my town?)

 

zonegran: review @ week one

Posted by River1924 on July 16, 2003, at 23:39:47

In reply to zonegran and bipolar II, posted by River1924 on July 16, 2003, at 23:19:57

As for the zonegran, it seems to give me a bit of nausea, headache and I sleep more. It reminds me of Lexapro in that respect. Zonegran increases serotonin transmission but I don't know if serotonin is the culprit. Otherwise, my moods seem more distinct to me. With this extra definition and consious awareness, I feel more in control. Instead of being swept away by the tide and drowning before I know it, I seem able to swim to dry land more easily. And to continue the metaphor, the sea itself (the moodscape) seems less unpredictable, the waves less fierce, the weather in a narrower range.

 

Re: zonegran: review @ week one

Posted by SLS on July 17, 2003, at 7:52:38

In reply to zonegran: review @ week one, posted by River1924 on July 16, 2003, at 23:39:47

Hi River.

I guess you're the lone pioneer with this drug. If I may ask, what condition(s) are you treating with Zonegran? My doctor mentioned Zonegran to me a few weeks ago, but I don't think he has used it yet. Your posts here are greatly appreciated. I hope the trend towards improvement you are experiencing now forecasts a remission.

Good luck.


- Scott

 

Re: zonegran: I take 100mgs/2x/day

Posted by NikiinNY on July 21, 2003, at 15:21:39

In reply to Re: zonegran: review @ week one, posted by SLS on July 17, 2003, at 7:52:38

Hi All,

I'm new here and came across this board while searching google for information on Zonegran.

I live in NY and most pdocs are prescribing it for mood stabilization in place of Neurontin, Depakote, etc.

I am not sure if anyone saw but there is a huge lawsuit regarding Neurontin. It was featured on Dateline, there may be information on NBC's website, anyway it basically said there shows no clinical information regarding its efficacy in bipolar disorder. There was more to the story...basically the makers of Neurontin paid outside companies to publish independent studies saying it was effective.

With that said, I haven't taken Neurontin since my pdoc introduced me to Zonegran about a year and a half ago.

I read the earlier posts and I haven’t experience any side effects on Zonegran (I am taking 100mgs 2x/day) except *weight loss*. Now, I'll take that side effect any day:)

It seems to be the "latest and greatest" drug here in NY but I guess like all the other "miracle pills", we'll have to wait and see.

Niki

 

Re: zonegran: I take 100mgs/2x/day

Posted by River1924 on July 21, 2003, at 16:23:24

In reply to Re: zonegran: I take 100mgs/2x/day, posted by NikiinNY on July 21, 2003, at 15:21:39

Great. I'm glad it works for you. Always gives me hope. As for me, I haven't decided.

It makes me itch and since I'm bipolar II, I'm more prone to depression than upswings. I'm not nauseaus or dizzy since I stopped my anti-depressant (I think zonegran was interacting with it.) But I haven't heard zonegran has any anti-depressant properties. Already people are asking me what is wrong with me, "you are so quiet." And since skipping the antidepressant I've already become a bit crabby. We'll see. I read zonegran improves over time. I've rarely found that in a med but this might be a first. I'm a bit sleepy but more organized on zonegran. It seems effective for some of my anxiety. We'll see. I have a feeling it ain't gonna work for me.

 

Re: zonegran: BPD dx (100 mgs 2x/day)

Posted by NikiinNY on July 21, 2003, at 17:20:54

In reply to Re: zonegran: I take 100mgs/2x/day, posted by River1924 on July 21, 2003, at 16:23:24

Hey, I just read your post. Although I understand you’re pessimistic about the Zonegran, I can only say to give it a fair trial and stick to your doctor's recommendations.

I don't take it for bipolar disorder. Rather, I have a dx on Axis II, Cluster B and it helps with the impulsiveness.

I definitely do have depressive "features" and have found that the Zonegran does help. I also experienced a similar problem combining it with an SSRI. Initially I was on Lexapro with Zonegran. I have a severe history of insomnia going back to age 7 (I am now 27). I found that for me, the Zonegran kept me awake and very alert of my moods and emotions. I tried Lezapro on its own and was not overwhelmingly pleased with the results. I can honestly and embarrassingly state that I have tried every SSRI and benzo out there. I am not one that is patient. Thus, if a med doesn't work within the first few weeks for me, I either stop taking it or make adjustments to my med regimen as I see fit. My point here is that I am not one to be dolling out advice:) telling you to give the Zonegran a chance. However, I can say that changing SSRI's while on it, greatly improved the benefits of the med for me.

 

Re: Zonegran Links

Posted by NikiinNY on July 21, 2003, at 17:27:16

In reply to Re: zonegran: I take 100mgs/2x/day, posted by River1924 on July 21, 2003, at 16:23:24

Here are some links that gives information (more then I have found elsewhere) on using Zonegran for psych purposes.

Hope it helps.

http://qualitycounts.com/drugs/zonegran(zonisamide).htm

 

Zonegran @ Week 2

Posted by River1924 on July 24, 2003, at 0:16:01

In reply to Re: Zonegran Links, posted by NikiinNY on July 21, 2003, at 17:27:16

I'm stopping the med. On the positive side, it has some effect on social anxiety. I seemed much less avoidant of people and normal day-to-day interactions. But I could only get the nausea to stop when I stopped my antidepressant and I quickly fell into a stuporous low. I may try it again someday but the itching is a big turn-off.

 

Re: zonegran and bipolar II/nausea/fatigue

Posted by tired10mom on July 24, 2003, at 12:14:35

In reply to zonegran and bipolar II/nausea/fatigue, posted by River1924 on July 15, 2003, at 18:44:47

My daughter was on Zonegran (the miracle drug) for
just two weeks before she had an allergic reaction to it.
It is a sulfonamide. Her body burned from the inside
out with second degree burns over 51% of her body,
and her mucous members burned from her mouth all the way
through to her anus and vagina. We spent three weeks in
June in the Burn Intensive Care Unit, and now that she is
home, I am bathing my 16-year-old daugther, soaking off
bandages, applying ointments, and putting dressings back on.
She has massive scarring on her back, chest, arms, buttocks,
and stomach. We are waiting on a compression suit that she
will wear for 6-9 months, if not longer. Then we can consult
with a plastic surgeon for reconstructive surgery.

Sometimes miracle drugs aren't all they're cracked up to be.
The thing that attracted my daughter to it was the weight loss
side effect since most of the other drugs cause weight gain.
The doctors and pharmacies tell you about the nausea, fatigue,
headaches, weight loss, drowsiness... You can live with those.
They don't tell you about Stevens-Johnson Syndrom or Toxic
Epidermal Necrolysis which are also know side effects. These are
the ones that will kill you. And your children.

Please be careful. I don't want anyone to ever go through what
we've experienced. Especially since the meds she was on were
working well except for the weight. And imagine my surprise to
find out that in Texas, for mental health issues, a 16-year-old
can make decisions about their own welfare and sign for themselves.

 

Zonegran...my new med

Posted by Heather S on July 24, 2003, at 12:29:09

In reply to Zonegran @ Week 2, posted by River1924 on July 24, 2003, at 0:16:01

I found this message board while searching for info on Zonegran, as my doctor just took me off my wellbutrin and replaced it with this. He's concerned that I may have temporal lobe epileptic seizures, so we're giving this a spin while we wait for test results. What a relief to see I'm not alone! I've been anti-social for weeks now, and it just isn't my personality! Hopefully this will be the light at the end of my tunnel of Hell. Keep the new posts comin!

 

Re: zonegran and bipolar II

Posted by tired10mom on July 24, 2003, at 12:36:47

In reply to zonegran and bipolar II, posted by River1924 on July 16, 2003, at 23:19:57

It is actually produced by a company called
Dainippon Pharmaceutical Co. Ltd. in Japan. It
was just approved by the FDA in March 2000, so it
is a relatively new drug. As a matter of fact,
the prescription labeling text was approved by the
FDA 10/7/02. If you look on the FDA's website you
can see why the letters are so small on the inserts.
It prints out something like 14 pages long!

 

Re: zonegran and bipolar II/nausea/fatigue

Posted by glc on October 9, 2003, at 20:44:33

In reply to Re: zonegran and bipolar II/nausea/fatigue, posted by tired10mom on July 24, 2003, at 12:14:35

Dear tired10mom,

I'm so sorry about what happened to your daughter. My Dr. just prescribed this drug to me and warned me to stop taking it if I felt itchy or developed a rash. I'm wondering, did your daughter develop a rash at first, or did the burning just start with no warning? You post prompted me to read the entire pamphlet about Zonegran put out by the company. The SJS and TEN are mentioned in there, but the exact nature of these syndrome are not described. You are right, the doctors and pharmacists should do a better job of informing patients. If I were you I would look into taking legal action against the Dr. who prescribed this drug and the drug company too.

 

Re: zonegran and bipolar II » tired10mom

Posted by katia on October 9, 2003, at 21:51:45

In reply to Re: zonegran and bipolar II, posted by tired10mom on July 24, 2003, at 12:36:47

Oh my goodness, I'm sorry to hear about your poor daughter! How awufl for you both!

Did she titrate up slowly? I've heard that with lamcital, if you titrate up too quickly this rash can occur.
Katia

 

Re: zonegran and bipolar II/nausea/fatigue

Posted by tired10mom on October 10, 2003, at 13:50:12

In reply to Re: zonegran and bipolar II/nausea/fatigue, posted by glc on October 9, 2003, at 20:44:33

> Dear tired10mom,
>
> I'm so sorry about what happened to your daughter. My Dr. just prescribed this drug to me and warned me to stop taking it if I felt itchy or developed a rash. I'm wondering, did your daughter develop a rash at first, or did the burning just start with no warning? You post prompted me to read the entire pamphlet about Zonegran put out by the company. The SJS and TEN are mentioned in there, but the exact nature of these syndrome are not described. You are right, the doctors and pharmacists should do a better job of informing patients. If I were you I would look into taking legal action against the Dr. who prescribed this drug and the drug company too.

She took Zonegran for about two weeks before anything started to happen. Then she started feeling like she had the flu with sore throat, headache, and ache and pains. At exactly two weeks she broke out in a light rash on her chest. By the next morning, she had hives one her chest, stomach, and upper back. We went to the doctor who told us she had a severe URI and allergic reaction to theh Zonegran. He gave her antibiotics, a shot of steroids, and a Medrol pack to continue taking at home. The next day she the hives had turned to solid red swollen from her next to mid-thigh, front and back. She could hardly walk. By the fourth day, she crawled out of bed our room to wake us up. She was having trouble breathing. Our PCP has urgent care hours on Saturday so we rushed to take her there. We cut the clothes she had worn to bed off of her because she was so swollen she was crying. I barely touched her with my nail and a substantial chunk of skin came off in my hand. There were small blisters forming on her shoulders. Her dad was going to carry her to the car, but she started screaming that it hurt to bad for him to touch her. By the time we got to the doctor, the small blisters had turned to large blisters. He gave her Demoral for pain and sent us directly to the hospital. When we got there, they were waiting with two guys to lift her out and lay her down so she wouldn't rip any more skin off...the blisters had run into each other to be giant blisters. Since Parkland has a phenomonal burn unit none of the other Dallas area hospitals are equipped to handle anything like this. Baylor gave her Morphine and arranged for an ambulance to transport her to Children's Medical Center until a bed opened up in the burn unit at Parkland. They gave her more Morphine in the ambulance and tied her to the gurney as securely as possible, but by the time we got there, a great portion of the skin had been ripped from her back. She was is ICU for 14 days living on feeding tubes, Morphine, and a variety of other IV fluids. Many of those days we didn't know if she would live or die. What they don't tell you about SJS/TEN is that only about 30% of the people who get it live, and of those that do, the majority are tragically disfigured by scarring. My daughter was lucky, if you can be lucky. The 51% of her body that is scarred doesn't include her face or eyes, and she didn't lose the use of any of her limbs. Unfortunately, being 16, it will be a long time before she recovers emotionally. As for taking legal action...you will find that it is extremely difficult to find anyone to testify against another doctor unless they have done something that is very apparent. We had a hard time even finding someone that would take the case. It was decided that we didn't have a case because the medical community felt that "occasionally everyone makes a mistake." Thanks for your concern and well wishes. She did feel amazingly better while she was on it. I hope you have better luck with it.

 

Re: zonegran and bipolar II/nausea/fatigue » tired10mom

Posted by katia on October 10, 2003, at 14:55:12

In reply to Re: zonegran and bipolar II/nausea/fatigue, posted by tired10mom on October 10, 2003, at 13:50:12

Dear Tired10Mom,
AGain, i'm sorry what happened to your poor daughter. But as you said, the positive side is she is alive and not scarred on her face and has use of her limbs.
In hindsight, do you think if you had gotten her to the hospital earlier (i.e. if the doctor had warned you IF ANY such rash occurs go to the hospital immediately and tell them it's probably SJS/TEN), do you think she may have not gone as far as she did with the severity of the burns?
Did she titrate up quickly on it for the initial two weeks?
blessings to you both,
katia


> > Dear tired10mom,
> >
> > I'm so sorry about what happened to your daughter. My Dr. just prescribed this drug to me and warned me to stop taking it if I felt itchy or developed a rash. I'm wondering, did your daughter develop a rash at first, or did the burning just start with no warning? You post prompted me to read the entire pamphlet about Zonegran put out by the company. The SJS and TEN are mentioned in there, but the exact nature of these syndrome are not described. You are right, the doctors and pharmacists should do a better job of informing patients. If I were you I would look into taking legal action against the Dr. who prescribed this drug and the drug company too.
>
> She took Zonegran for about two weeks before anything started to happen. Then she started feeling like she had the flu with sore throat, headache, and ache and pains. At exactly two weeks she broke out in a light rash on her chest. By the next morning, she had hives one her chest, stomach, and upper back. We went to the doctor who told us she had a severe URI and allergic reaction to theh Zonegran. He gave her antibiotics, a shot of steroids, and a Medrol pack to continue taking at home. The next day she the hives had turned to solid red swollen from her next to mid-thigh, front and back. She could hardly walk. By the fourth day, she crawled out of bed our room to wake us up. She was having trouble breathing. Our PCP has urgent care hours on Saturday so we rushed to take her there. We cut the clothes she had worn to bed off of her because she was so swollen she was crying. I barely touched her with my nail and a substantial chunk of skin came off in my hand. There were small blisters forming on her shoulders. Her dad was going to carry her to the car, but she started screaming that it hurt to bad for him to touch her. By the time we got to the doctor, the small blisters had turned to large blisters. He gave her Demoral for pain and sent us directly to the hospital. When we got there, they were waiting with two guys to lift her out and lay her down so she wouldn't rip any more skin off...the blisters had run into each other to be giant blisters. Since Parkland has a phenomonal burn unit none of the other Dallas area hospitals are equipped to handle anything like this. Baylor gave her Morphine and arranged for an ambulance to transport her to Children's Medical Center until a bed opened up in the burn unit at Parkland. They gave her more Morphine in the ambulance and tied her to the gurney as securely as possible, but by the time we got there, a great portion of the skin had been ripped from her back. She was is ICU for 14 days living on feeding tubes, Morphine, and a variety of other IV fluids. Many of those days we didn't know if she would live or die. What they don't tell you about SJS/TEN is that only about 30% of the people who get it live, and of those that do, the majority are tragically disfigured by scarring. My daughter was lucky, if you can be lucky. The 51% of her body that is scarred doesn't include her face or eyes, and she didn't lose the use of any of her limbs. Unfortunately, being 16, it will be a long time before she recovers emotionally. As for taking legal action...you will find that it is extremely difficult to find anyone to testify against another doctor unless they have done something that is very apparent. We had a hard time even finding someone that would take the case. It was decided that we didn't have a case because the medical community felt that "occasionally everyone makes a mistake." Thanks for your concern and well wishes. She did feel amazingly better while she was on it. I hope you have better luck with it.

 

Re: zonegran and bipolar II/nausea/fatigue

Posted by SLS on October 10, 2003, at 17:17:27

In reply to Re: zonegran and bipolar II/nausea/fatigue, posted by tired10mom on October 10, 2003, at 13:50:12

> > Dear tired10mom,
> >
> > I'm so sorry about what happened to your daughter. My Dr. just prescribed this drug to me and warned me to stop taking it if I felt itchy or developed a rash.


Hi.

I developed severe itching after taking Zonegran for two weeks. My doctor had me discontinue it. I also experienced fatigue, malaise, muscle weekness, and some mild aches and pains. It looks like these things aren't so rare.


- Scott

 

Re: zonegran and bipolar II/nausea/fatigue

Posted by sarita0001 on October 11, 2003, at 8:59:31

In reply to Re: zonegran and bipolar II/nausea/fatigue, posted by tired10mom on October 10, 2003, at 13:50:12

Hello-

I am sorry to hear about what happened to your daughter. I hope she is doing better. I was diagnosed bipolar at 17 and was started on lithium and continued on that for 7 years. Lithium has less chance for adverse effects like the anticonvulsants but every one handles medicine differently. Doctors will tell you that it is not used as often but historically has always been the first choice for bp.

Earlier this year, I took Topamax(an anticonvulsant) and experienced side effects which I was told were rare but found out from my new doctor that they are really not. The key to having less side effects is the fewer medications one takes. My body was so used to lithium when I added Topamax it threw everything off. I grew a significant amount of hair on my face (which is costing me up to 2000 to laser off) and extra body hair. So i know what it is like regarding self-esteem as a young woman. As time goes on and the scars fade your daughter will get better. Good luck to you and if you have any questions I am here.

Sara

 

Re: zonegran and bipolar II/nausea/fatigue

Posted by tired10mom on October 12, 2003, at 18:01:14

In reply to Re: zonegran and bipolar II/nausea/fatigue » tired10mom, posted by katia on October 10, 2003, at 14:55:12

She was still on the initial lowest dose and was scheduled to be increased the following week if everything was going well. However, she was also left of the depakote at the same time. As far as going to the hospital sooner, if it is truly an SJS/TEN reaction as hers was, it wouldn't have mattered. There is nothing that can be done to stop it. It has to run its course. Were there something that could have been done to stop it, they would have stopped it the first day they were sure what it was. Had it be simply an allergic reaction, the benedryl and steriods would have taken care of it quite well.

 

Re: zonegran and bipolar II/nausea/fatigue » tired10mom

Posted by katia on October 13, 2003, at 1:35:50

In reply to Re: zonegran and bipolar II/nausea/fatigue, posted by tired10mom on October 12, 2003, at 18:01:14

Thanks for getting back to me.
It's so scary - SJS, and the fact that nothing can stop it and only 30% of people survive it. I am also on Depakote and have just started Lamictal; of which both have risk of this. I'm 33 and I think younger people have a greater risk somehow. The thought of it makes me want to quit. But then the thought of living like I have been makes me want to take the chance.
Many blessings to you and your daughter.
Katia

 

Topamax Side Affects!

Posted by California_Princess on October 15, 2003, at 20:29:59

In reply to Re: zonegran and bipolar II/nausea/fatigue » tired10mom, posted by katia on October 13, 2003, at 1:35:50

Hello!
Tired10mom, I am soooo sorry about your daughter. As I read the post I was crying for you and her and I hope this will be behind you soon!

I was recently diagnosed with Bi-Polar Disorder, (after being misdiagnosed 7 years ago with Major Depressive Disorder) I also have an Anxiety Disorder, both of which I've had all my life, but just thought I was a bad person and loser. I was so happy to finally know what was wrong with me, but now come all the drugs.

Because I'm 140 pounds over weight I told my PDoc that I would not take any drug that would cause weight gain. He started me out with Topamax because of it's weight loss properties. Unfortunately after about 3 weeks I had to stop taking it because at only 75 mgs, (I stated out with 25 mgs) my lungs hurt so badly it was hard for me to breath and crazy racing thoughts made it impossible to sleep.
The irritability, being unable to concentrate and the general "dumbness" (memory loss, slurred speech or not being able to say one half way intelligent thing, stuttering...) was something that I could live with because I was hoping that it would go away.

I failed a test for a job that I needed, I lost my car in the parking structure, (this was a big city) and I got lost on the freeway and ended up in a neighboring city with no idea how to get home!!! However the sore lungs and insomnia I couldn't deal with. I've been off Topamax for 5 days now and my lungs just stopped hurting yesterday. My appetite came back today.... :O( My sleeping has almost returned to normal and mental fog has lifted.

Unfortunately the day after I quit taking the med, (and I was only on it for about 3 weeks) I plunged into a VERY deep depression and I think if my husband would have left me alone I would have tried to kill myself. After about a day and a half it went a way.

So now I'm thinking about Zonegran.... I read that it can cause Kidney stones, Irritability, and Weight loss so I'm wondering how much this drug is like Topamax because those are the side affects of it too. However I haven't read so much about the loss of the ability to think and reason, ("dumbness") which was a big problem for a lot of folks with the Topamax.

I was thinking about asking my PDoc about it on my next appointment Monday, but after hearing about what happend to your daughet, Tired10mom, I'm scared now.

I'm such a baby, but I get panic attacks when I have to take a medicine that I'm scared to take.... :O(

I so much want this sickness to end or get better, I'm tired of living like this for 35 years... but now with all these drugs avalible, and some of the dangerous, it seems hopeless!
Melissa

 

Zonegram stats for the rash anyone???? » California_Princess

Posted by katia on October 15, 2003, at 22:55:11

In reply to Topamax Side Affects!, posted by California_Princess on October 15, 2003, at 20:29:59

Hi Cal. Dreamer,
Yes, I agree it seems ALMOST hopeless. I go bacck and forth - should I take meds and risk these awful results or live as I have been? I always come back to, I can't live like I have been and I need help. I too am BP, I think II/mixed/rapid cycler? who knows> I've had so many different ways in which this "disorder" has manifested itself over the years - had one classic mania (was never hospitalized) high 15 yrs. ago (I was 17/18), and then panic anxiety pre that and post that - serious chronic depression interspersed with either mania or hypomania for the hellish duration of my adult and teenage life (I'm 33). Anyway, finally a year ago, I finally realized how i was, was not "normal" and could possibly be depression? I sought help. I was mis-dxed for a year too as double depressed until finally none of the ADs worked on me. I've just started my own trial and error with the mood stabilizers. I'm going off of Depakote, going onto Lamcital (scared about the rash!) and probably combining Lithium.
I thought about Topamax too. Sorry to hear you had bad luck with that.
the stats with the rash and lamictal are 1 in 1,000 (if you titrate up slowly and are over 16). I wonder what the stats are on Zonegram? Is it more dangerous? anyone know?
Katia

 

Re: Topamax Side Affects!

Posted by tired10mom on October 16, 2003, at 9:05:56

In reply to Topamax Side Affects!, posted by California_Princess on October 15, 2003, at 20:29:59

I've been taking Topomax for 3 years to prevent migraines. I must say, at first I had the same side effects you are talking about that I thought would drive me crazy. I, too, started at 25mg, but over time have built up to 500mg. The "dumbness" as you put it went away at about 125mg if I remember correctly. My doc just temporarily gave me something to help me sleep. I went from having migraines 3/week to about 1/month and now maybe 4/year. And I lost about 40 lbs.

As for the Zonegran, I don't want to anyone away from it that it might be beneficial for. It worked extremely well for what it was being used for. Unfortunately, a lot of times, people don't think about the fact that these type of drugs can and do have substances in them like sulpha that people are allergic to, that are more commonly found in antibiotics. We had a known history of a sulpha allergy in our family for generations, and Jennifer's doc gave her the drug anyway knowing this. Neither he nor the pharmacist told us sulpha was a compound in Zonegran or we wouldn't have given it to her. Now we ALWAYS request the drug inserts, and we know how to read them.

Part of being bipolar for Jennifer was never feeling that anyone really loved and accepted her. She was always working too hard to fit in. After going through this, she knows how many people really do love her and care about her. She has found that some people she thought were her friends really weren't. But she also found that there were more people than she new cared about her. People came out of the woodwork to see if they could help, if she needed anything, if she just wanted to watch a movie or talk. She feels more at ease and secure with herself without having to keep up a facade and be one of the "cool kids" than she's ever felt before. It's hard enough to be a teenager these days with all the peer pressure that goes along with it, without adding second degree burn scars on both arms and on your back and chest. Between her new friends, her family, her psychiatrist, and her "very cool" psychologist, she has decided that if someone doesn't like the way she looks, it is their problem.

Please don't give up, it is never hopeless. Over the last seven years, our family has been through some extremely tramatic and sometimes tragic events. But something good comes out of every situation. Sometimes you just have to look really hard for it. But more than that, you have to WANT to find it. Believe in yourself. Believe in your husband. Believe in your love and life together. Otherwise, all the meds in the world won't help.


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