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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by bee on September 25, 2000, at 17:37:28
Update. I was trying doxepin along with elavil to get away from the cravings of elavil but did not work as I got even more cravings with this combo! I switched to trimipramine (25 mg) and elavil (60 mg) but found this combo not working also (excessive flushing, sweating - felt like menopause but I'm not ready for that yet, thank you!!).
My doctor wrote a prescription for Ludiomil starting at 10 mg. once daily, increasing to 3 times daily over a period of weeks. This would also be taken along with 60 or 70 mg. elavil to help me sleep and later, hopefully decrease the elavil so the food cravings lessen.
Any words of wisdom or caution?
Thanks
bee
Posted by SLS on September 25, 2000, at 20:11:03
In reply to Ludiomil profile, please??, posted by bee on September 25, 2000, at 17:37:28
> Update. I was trying doxepin along with elavil to get away from the cravings of elavil but did not work as I got even more cravings with this combo! I switched to trimipramine (25 mg) and elavil (60 mg) but found this combo not working also (excessive flushing, sweating - felt like menopause but I'm not ready for that yet, thank you!!).
>
> My doctor wrote a prescription for Ludiomil starting at 10 mg. once daily, increasing to 3 times daily over a period of weeks. This would also be taken along with 60 or 70 mg. elavil to help me sleep and later, hopefully decrease the elavil so the food cravings lessen.
>
> Any words of wisdom or caution?
>
> Thanks
>
> bee
Hi Bee.I think that it is important to take into consideration that Elavil might produce a conflict or an exaggeration of the side effects of any other drugs you may be taking. Both Ludiomil (maprotiline) and Elavil (amitriptyline) inhibit the reuptake of norepinephrine (NE) and produce anticholinergic side effects. Perhaps your flushing and sweating when adding Surmontil (trimipramine) to Elavil was caused by such a reaction between these two anticholinergic drugs. Maybe things would be less complicated if you were to choose another drug to help you sleep.
Of course, it is also possible that the combination of Elavil + Ludiomil will work better than Ludiomil by itself. Either way, it is important to take into consideration any cardiac problems you may have as both of these drugs are can be cardiotoxic.
I have never taken Ludiomil to be able to describe its side effects (I think I'll add this drug to my short list). However, you should expect side effects that are similar to those of Elavil: dry-mouth, constipation, sweating, increased heart-rate, blurred vision, and difficulty urinating. It is difficult to predict whether you will experience any of these or how long they might last.
Drug Monograph: http://www.mentalhealth.com/drug/p30-l04.html
Good luck.
- Scott
Posted by bee on September 25, 2000, at 21:08:08
In reply to Re: Ludiomil profile, please??, posted by SLS on September 25, 2000, at 20:11:03
Scott
Thanks for the info. I was thinking about combos affecting each other. Although, I did not have this flushing, etc... while on doxepin and elavil so maybe, it was just the combo of trimipramine and elavil that did not agree with me.
In my dream world, I will find an anti-depressent that has no side effects and keeps depression away. Of course, in the real world, I doubt this can happen for me. I hope that maybe Ludiomil will work for my insomnia, have less side effects than the elavil and then maybe, I can just be on one med. Let's hope!!
Again, thanks.
bee
>
> I think that it is important to take into consideration that Elavil might produce a conflict or an exaggeration of the side effects of any other drugs you may be taking. Both Ludiomil (maprotiline) and Elavil (amitriptyline) inhibit the reuptake of norepinephrine (NE) and produce anticholinergic side effects. Perhaps your flushing and sweating when adding Surmontil (trimipramine) to Elavil was caused by such a reaction between these two anticholinergic drugs. Maybe things would be less complicated if you were to choose another drug to help you sleep.
>
> Of course, it is also possible that the combination of Elavil + Ludiomil will work better than Ludiomil by itself. Either way, it is important to take into consideration any cardiac problems you may have as both of these drugs are can be cardiotoxic.
>
> I have never taken Ludiomil to be able to describe its side effects (I think I'll add this drug to my short list). However, you should expect side effects that are similar to those of Elavil: dry-mouth, constipation, sweating, increased heart-rate, blurred vision, and difficulty urinating. It is difficult to predict whether you will experience any of these or how long they might last.
>
> Drug Monograph: http://www.mentalhealth.com/drug/p30-l04.html
>
> Good luck.
>
>
> - Scott
Posted by Sunnely on September 25, 2000, at 23:47:39
In reply to Ludiomil profile, please??, posted by bee on September 25, 2000, at 17:37:28
> My doctor wrote a prescription for Ludiomil starting at 10 mg. once daily, increasing to 3 times daily over a period of weeks. This would also be taken along with 60 or 70 mg. elavil to help me sleep and later, hopefully decrease the elavil so the food cravings lessen.
>
> Any words of wisdom or caution?
>
> Thanks
>
> bee
Dear bee,I agree with Scott regarding the potential for increased anticholinergic and cardiotoxic effects with the combined use of amitriptyline (Elavil) and maprotiline (Ludiomil). If I may add, the concomitant use of these drugs also increases the risk for seizures. Therefore, caution should be exercised when combining these drugs.
BTW, although similar in mechanism of action and side-effect profile, Elavil is a tricyclic antidepressant while Ludiomil is a tetracyclic antidepressant.
Posted by Cindy W on September 26, 2000, at 0:20:39
In reply to Ludiomil profile, please??, posted by bee on September 25, 2000, at 17:37:28
> Update. I was trying doxepin along with elavil to get away from the cravings of elavil but did not work as I got even more cravings with this combo! I switched to trimipramine (25 mg) and elavil (60 mg) but found this combo not working also (excessive flushing, sweating - felt like menopause but I'm not ready for that yet, thank you!!).
>
> My doctor wrote a prescription for Ludiomil starting at 10 mg. once daily, increasing to 3 times daily over a period of weeks. This would also be taken along with 60 or 70 mg. elavil to help me sleep and later, hopefully decrease the elavil so the food cravings lessen.
>
> Any words of wisdom or caution?
>
> Thanks
>
> beebee, I took Ludiomil a long time ago, after imipramine (Tofranil) and Sinequan and before Prozac. I quit the imipramine because of the report of heart problems in some, and I quit Sinequan because I couldn't keep awake. With Prozac, I couldn't reach orgasm and lost all desire. With Ludiomil, I was so spaced out, I went home on afternoon with my groceries, went up to what I thought was my house (why is that gold cadillac parked in my driveway??) and tried to open the front door. Then I wondered, why are those people in my house? I had gone to the wrong house!!! So I stopped the Ludiomil. Hope you have a better experience than I did. Med responses are so different, for different people! Hope it works out for you.-Cindy W
Posted by Sigolene on September 26, 2000, at 2:00:47
In reply to Ludiomil profile, please??, posted by bee on September 25, 2000, at 17:37:28
Hi bee,
I took Ludiomil 3 years ago, during 2 years as monotherapy. I had to stop it due to too much weight increase.
I also had strong constipation.
But on the positive side, Ludiomil is has a strong anti depressant effect, and I could sleep better than I never slept before. But I think if you take Ludiomil, you don't need to add other AD with it. And be careful ot to eat to much.
For the sedating effect, it's the same as Remeron or Desyrel for example. But Ludiomil acts only on NE.
Sigolene
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