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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by jedi on November 9, 2012, at 22:55:37
Hi Guys,
Haven't been around much lately but thought I should mention this again. When you are taking MAOIs you have to take your level of self education up a level. A very limited number of medical professionals have any knowledge at all of this class of medication.I went to the initial care clinic today with what they diagnosed as a viral infection (cold). The doctor knew I was taking Nardil but still suggested I take a cough syrup with dextromethorphan. I explained to him that I couldn't take that with Nardil. He asked why not, and I told him that it could possibly kill me. I don't think he really believed me, but hopefully he went and looked it up! Probably not.
Be well and be educated,
JediReference:
Possible Lethal Reaction Between Nardil and Dextromethorphan
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1930348/
Posted by Phillipa on November 9, 2012, at 23:12:17
In reply to MAOIs and self education, posted by jedi on November 9, 2012, at 22:55:37
Jedi just wanted to say hi and hope all is well with you other than the cold. Phillipa
Posted by ChicagoKat on November 10, 2012, at 8:42:22
In reply to MAOIs and self education, posted by jedi on November 9, 2012, at 22:55:37
Thanks Jedi, you are so right.
While I've been going through horrible nardil withdrawal this week, I made it very clear to my husband that if I became inconherent and had to go to the hospital that is was extraordinarily important for him to tell the people there that I am on an MAOI, and not only that, to stress that giving me certain drugs could literally kill me. I told him it's completely possible that even if you tell them I'm on an MAOI they may have absolutely no clue what that implies. I really need to get one of those medic alert bracelets, but it scares me that even if I wear one that say I'm on an MAOI, I could still end up being given the wrong drug.
Thanks for your post....it was a very important one.
Kat
Posted by Roslynn on November 10, 2012, at 15:33:37
In reply to MAOIs and self education, posted by jedi on November 9, 2012, at 22:55:37
This is very true and it scares me, if I ever were to be in the hospital, unconscious, etc. Do they know how to treat a hypertensive crisis?
Roslynn
> Hi Guys,
> Haven't been around much lately but thought I should mention this again. When you are taking MAOIs you have to take your level of self education up a level. A very limited number of medical professionals have any knowledge at all of this class of medication.
>
> I went to the initial care clinic today with what they diagnosed as a viral infection (cold). The doctor knew I was taking Nardil but still suggested I take a cough syrup with dextromethorphan. I explained to him that I couldn't take that with Nardil. He asked why not, and I told him that it could possibly kill me. I don't think he really believed me, but hopefully he went and looked it up! Probably not.
> Be well and be educated,
> Jedi
>
> Reference:
> Possible Lethal Reaction Between Nardil and Dextromethorphan
> http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1930348/
>
Posted by emmanuel98 on November 10, 2012, at 19:25:54
In reply to MAOIs and self education, posted by jedi on November 9, 2012, at 22:55:37
I had to explain to my dentist that MAOIs were dangerous with epinephrine. He at first didn't take it seriously and kept forgetting and wanting to give me novacaine. I don't know if he looked it up, but he has been very careful since then. Unfortunately, I've had to see a lot of him because I had two crowns, including one that fell out.
Posted by emmanuel98 on November 10, 2012, at 19:27:15
In reply to Re: MAOIs and self education, posted by Roslynn on November 10, 2012, at 15:33:37
I where a medic alert bracelet for parnate. The biggest danger in an ER is demerol.
Posted by jedi on November 10, 2012, at 20:22:54
In reply to Re: MAOIs and self education, posted by emmanuel98 on November 10, 2012, at 19:27:15
> I where a medic alert bracelet for parnate. The biggest danger in an ER is demerol.
Yes, if you wear the medic alert, which is is a very good idea; it should say "NO MEPERIDINE", along with the "TAKING MAOI". If you are unconscious in an accident or in the ER, this may just save your life. I put mine in my cell phone and on my driver's license, but I know the medic alert bracelet is a much better idea.
It seems to me the tyramine content of our foodstuffs is getting lower. As long as you are fairly careful, the risk of a hypertensive reaction is minimal. However, serotonin syndrome is potentially deadly and mixing the serotonin drugs with MAOIs is asking for the long dirt nap! All phenylpiperidine opioids (meperidine, methadone, tramadol) can react with the irreversible MAOIs. I've used phenelzine with many opioids that do not affect serotonin, no problem at all. Codeine, and many other opioids, that do not affect serotonin are fine with MAOIs. There is a lot of misinformation and you have to wade through the chafe!
Be safe,
JediReference:
MAO inhibitor: meperidine toxicity
http://www.openanesthesia.org/index.php?title=MAO_inhibitor:_meperidine_toxicity
Posted by jono_in_adelaide on November 11, 2012, at 19:02:17
In reply to Re: MAOIs and self education, posted by jedi on November 10, 2012, at 20:22:54
In Australia, people being treated with MAOI's are usualy given a card by the pharmacist stating thatt hey are on drug XXX, listing the foods and drugs they should avoid, and giving advice to emergency doctors as to what they can and cant be given.
Posted by jono_in_adelaide on November 11, 2012, at 19:06:07
In reply to Re: MAOIs and self education, posted by jedi on November 10, 2012, at 20:22:54
But the medic alert bracelet sounds like an excelent idea, I'd encourage anybody taking an MAOI to get one.
Posted by PetersKeys on September 15, 2014, at 18:14:40
In reply to Re: MAOIs and self education, posted by jedi on November 10, 2012, at 20:22:54
Methadone is a Diphenylheptane derivative, not a phenylpiperidine derivative like Meperidine and Fentanyl
Hence methadone is a safe drug to take with parnate. I know someone who is on methadone and is on parnate.
"CONTRAINDICATED: The coadministration of narcotic analgesics and monoamine oxidase inhibitors (MAOIs) may rarely result in hypotension, respiratory depression, or coma. The mechanism is unknown but may be related to additive CNS and respiratory depressant effects. Rare case reports of severe hypotensive reactions have included propoxyphene (with multiple medications), morphine, and methadone, although others have reported the safe use of MAOIs with narcotic analgesics including methadone and morphine"
This is the end of the thread.
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