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Re: MAOIs and self education

Posted by PetersKeys on September 15, 2014, at 18:14:40

In reply to Re: MAOIs and self education, posted by jedi on November 10, 2012, at 20:22:54

Methadone is a Diphenylheptane derivative, not a phenylpiperidine derivative like Meperidine and Fentanyl

Hence methadone is a safe drug to take with parnate. I know someone who is on methadone and is on parnate.

"CONTRAINDICATED: The coadministration of narcotic analgesics and monoamine oxidase inhibitors (MAOIs) may rarely result in hypotension, respiratory depression, or coma. The mechanism is unknown but may be related to additive CNS and respiratory depressant effects. Rare case reports of severe hypotensive reactions have included propoxyphene (with multiple medications), morphine, and methadone, although others have reported the safe use of MAOIs with narcotic analgesics including methadone and morphine"


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URL: http://www.dr-bob.org/babble/20140914/msgs/1071181.html