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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by Mistermindmasta on March 31, 2011, at 10:31:43
Wow it's been an eternity since I posted on here...
Anyway... been on Nuvigil for 6 months now. I find it to be decent. Biggest problem is the side effects. It supposedly has a super long half life of 12 hrs. I think thats why Im having these side effects. But, in the AM when I take like 75 mgs, I feel pretty good. Nice focus, decent motivation, feeling awake, although it doesnt appear to increase physical energy the wake amphetamines do or caffeine, it definitely increases focus and motivation. Then around 3 hrs after that first dose, I start feeling a hair of dysphoria which makes it difficult to focus to a small extent. Then, around 11 I take another 25 to 75 mgs. At that point im ok for an hour or two and after that I start feeling kinda tweaked out and just really stressed out and crappy. I do find that waiting to take the second dose til after lunch seems to bombard my brain with too much stimulation over too long of a period of time which causes that stressed out feeling. When I take like 50 mg at 8am and then another 50 mg at 10am, after lunch I don't seem to get that overly stressed out feeling.
See, with amphetamines, I don't get this stressed out feeling AT ALL. I think it has to do w/ the shorter half life. And with amphs, I get a lot more calm focus. Whereas nuvigil feels like a real stimulant and does not induce a calm focus. Nuvigil to me is somewhere in between adderall and caffeine. Caffeine produces too much physical stimulation like shakiness, anxiety, etc that nuvigil doesnt cause. So that's great. But I want to avoid the dysphoria that happens after lunch. Any suggestions?? And has this happened to other people as well??
The most obvious suggestion is for me to take the small dose at 8 and then the other small dose at like 10 rather than waiting til after lunch. I think when I take it after lunch, theres just SO much stimulation for such a long period of time w/ the long half life that my brain doesn't calm down til like 10pm. Does that line of logic make sense? Do other ppl agree that my side effects may be related to the ultra long half life?
I take nuvigil for fatigue, so I guess it's kind of off label. I think I'd rather get adderall, but I think that would require all kinds of tests and whatnot and idk that my family doc can prescribe adderall. Whereas I can pretty much get as much nuvigil as I want with little effort.
Anyone else feels those same effects and find a nice way to deal w/ the stressed out feeling??
Thanks in advance!!
Posted by jjjaspar on April 2, 2011, at 11:39:21
In reply to Nuvigil side effects compared to amphetamines, posted by Mistermindmasta on March 31, 2011, at 10:31:43
Provigil is the shorter-acting version.
They do make some people feel stressed-out just like Wellbutrin/bupropion causes that feeling in some people. But for others, these are just right.
Rhodiola can give some people a boost similar to Wellbutrin but not nearly as strong as Provigil or Nuvigil.
Posted by desolationrower on April 2, 2011, at 15:04:50
In reply to Re: Nuvigil side effects compared to amphetamines, posted by jjjaspar on April 2, 2011, at 11:39:21
maybe just make sure you take a break to sit and relax?
-d/r
Posted by mtdewcmu on April 2, 2011, at 18:41:19
In reply to Nuvigil side effects compared to amphetamines, posted by Mistermindmasta on March 31, 2011, at 10:31:43
I had a prescription for Provigil a few years ago, and I had high hopes for it, because it was new and was supposed to deliver the benefits of amphtetamine with less side effects. But I ended up deciding that it was a crummy drug. I held on to the last couple dozen pills until they expired and then threw them out.
Posted by ihatedrugs on April 3, 2011, at 23:50:28
In reply to Nuvigil side effects compared to amphetamines, posted by Mistermindmasta on March 31, 2011, at 10:31:43
> Wow it's been an eternity since I posted on here...
>
> Anyway... been on Nuvigil for 6 months now. I find it to be decent. Biggest problem is the side effects. It supposedly has a super long half life of 12 hrs. I think thats why Im having these side effects. But, in the AM when I take like 75 mgs, I feel pretty good. Nice focus, decent motivation, feeling awake, although it doesnt appear to increase physical energy the wake amphetamines do or caffeine, it definitely increases focus and motivation. Then around 3 hrs after that first dose, I start feeling a hair of dysphoria which makes it difficult to focus to a small extent. Then, around 11 I take another 25 to 75 mgs. At that point im ok for an hour or two and after that I start feeling kinda tweaked out and just really stressed out and crappy. I do find that waiting to take the second dose til after lunch seems to bombard my brain with too much stimulation over too long of a period of time which causes that stressed out feeling. When I take like 50 mg at 8am and then another 50 mg at 10am, after lunch I don't seem to get that overly stressed out feeling.
>
> See, with amphetamines, I don't get this stressed out feeling AT ALL. I think it has to do w/ the shorter half life. And with amphs, I get a lot more calm focus. Whereas nuvigil feels like a real stimulant and does not induce a calm focus. Nuvigil to me is somewhere in between adderall and caffeine. Caffeine produces too much physical stimulation like shakiness, anxiety, etc that nuvigil doesnt cause. So that's great. But I want to avoid the dysphoria that happens after lunch. Any suggestions?? And has this happened to other people as well??
>
> The most obvious suggestion is for me to take the small dose at 8 and then the other small dose at like 10 rather than waiting til after lunch. I think when I take it after lunch, theres just SO much stimulation for such a long period of time w/ the long half life that my brain doesn't calm down til like 10pm. Does that line of logic make sense? Do other ppl agree that my side effects may be related to the ultra long half life?
>
> I take nuvigil for fatigue, so I guess it's kind of off label. I think I'd rather get adderall, but I think that would require all kinds of tests and whatnot and idk that my family doc can prescribe adderall. Whereas I can pretty much get as much nuvigil as I want with little effort.
>
> Anyone else feels those same effects and find a nice way to deal w/ the stressed out feeling??
> Thanks in advance!!Nuvigil worked somewhat for my fatigue but adderall really helps get me off the hump and get things done. And weirdly enough it relaxes me and puts me in a positive mood whereas nuvigil did not. I don't understand what the big deal with prescribing adderall is. After all, so many kids take them. It's so much easier to get pain killers and tranquilizers than amphetamines. These are a godsend for many who suffer from extreme fatigue. Vyvanse is another option which works pretty well.
Posted by floatingbridge on April 7, 2011, at 1:40:52
In reply to Nuvigil side effects compared to amphetamines, posted by Mistermindmasta on March 31, 2011, at 10:31:43
I gave up provigil because it invoked dysphoric thought and that invokes dysphoria. I hated it. Gave it all back. My pdoc had never heard of such a thing.
I did compare it to dexedrine. In fact, I overlapped the two for a very brief time. Couldn't make the provigil work.
I know you are discussing nuvigil. Wanted to pipe up when I read the word
dysphoria.
Posted by floatingbridge on April 7, 2011, at 2:30:41
In reply to Nuvigil side effects compared to amphetamines, posted by Mistermindmasta on March 31, 2011, at 10:31:43
I gave up provigil because it invoked dysphoric thought and that invokes dysphoria. I hated it. Gave it all back. My pdoc had never heard of such a thing.
I did compare it to dexedrine. In fact, I overlapped the two for a very brief time. Couldn't make the provigil work.
I know you are discussing nuvigil. Wanted to pipe up when I read the word
dysphoria.
Posted by Petrucci914 on April 8, 2011, at 15:56:53
In reply to Re: Nuvigil side effects compared to amphetamines » Mistermindmasta, posted by floatingbridge on April 7, 2011, at 2:30:41
I'm giving Nuvigil a second run right now. I've had varying experiences with Stimulants/Wakefullness agents. Some days they would work great, other days I'd have dysphoria, and other days it'd make me extremely tired. Getting off of pure stimulants is pure hell as well. I seem to be doing better this time either because I'm starting at a lower dose or because I am combining it with an antidepressant that has at least worked somewhat.
I've tried Vyvanse, Concerta, Provigil, and Wellbutrin. Wellbutrin worked great for about 6 months and then pooped out. Vyvanse was great for a month but then made me feel worse and getting off of it took a month and a half before I could somewhat pull myself out of that dopamine rebound.
Posted by mtdewcmu on April 8, 2011, at 20:28:24
In reply to Re: Nuvigil side effects compared to amphetamines, posted by Petrucci914 on April 8, 2011, at 15:56:53
> I'm giving Nuvigil a second run right now. I've had varying experiences with Stimulants/Wakefullness agents. Some days they would work great, other days I'd have dysphoria, and other days it'd make me extremely tired. Getting off of pure stimulants is pure hell as well. I seem to be doing better this time either because I'm starting at a lower dose or because I am combining it with an antidepressant that has at least worked somewhat.
>
> I've tried Vyvanse, Concerta, Provigil, and Wellbutrin. Wellbutrin worked great for about 6 months and then pooped out. Vyvanse was great for a month but then made me feel worse and getting off of it took a month and a half before I could somewhat pull myself out of that dopamine rebound.What were you using stimulants for? ADD? Depression?
Wellbutrin helped a lot with my concentration for a while, but it pooped out for me, also, after about 6-12 months. I am still hoping to try Dexedrine or Vyvanse.
Posted by floatingbridge on April 9, 2011, at 8:24:10
In reply to Re: Nuvigil side effects compared to amphetamines, posted by Petrucci914 on April 8, 2011, at 15:56:53
Posted by Petrucci914 on April 9, 2011, at 22:16:33
In reply to Re: Nuvigil side effects compared to amphetamines » Petrucci914, posted by mtdewcmu on April 8, 2011, at 20:28:24
For Depression, I don't have ADD.
I was on Vyvanse also. Had a great month on it followed by some of the worst depression of my life.
This is the end of the thread.
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