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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by aazospiro on January 29, 2004, at 9:06:50
Has anyone ever heard about using low dose Prolopa [LEVODOPA/BENSERAZIDE] for cyclothymia and other mood disorders?
I have heard about success stories, though few. In particular I have a friend who has suffered from chronic mood swings, irritabilty, anxiety, depression, and impaired attention, anhedonia and insomnia and has had about 80 % relief from 62.5 mg of Prolopa twice daily with Pindolol 2.5 mg 3 times a day. I would really like to know.
I would appreciate your feedback as well Dr. Bob
Thanks
Posted by Chairman_MAO on January 29, 2004, at 20:34:38
In reply to SINEMET FOR CYCLOTHYMIA, posted by aazospiro on January 29, 2004, at 9:06:50
Use of l-dopa in psychiatry is questionable, IMHO. Perhaps with careful titration it could be useful, as in the case of your friend, but why bother with its wacky pharmacokinetics and possible neurotoxicity when there are safer, possibly neuroprotective dopamine agonists available which have been found in studies to be useful in depressive syndromes: pramipexole, ropinirole, cabergoline, and, to a lesser extent bromocriptine (which has serotonergic effects, too) and pergolide? And then there is selegiline, but I'd think a pure agonist would be a better choice.
Use whatever works and has a reasonable margin of safety, I know I'd think long and hard about putting l-dopa into MY body ...
This is the end of the thread.
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