Posted by Chairman_MAO on January 29, 2004, at 20:34:38
In reply to SINEMET FOR CYCLOTHYMIA, posted by aazospiro on January 29, 2004, at 9:06:50
Use of l-dopa in psychiatry is questionable, IMHO. Perhaps with careful titration it could be useful, as in the case of your friend, but why bother with its wacky pharmacokinetics and possible neurotoxicity when there are safer, possibly neuroprotective dopamine agonists available which have been found in studies to be useful in depressive syndromes: pramipexole, ropinirole, cabergoline, and, to a lesser extent bromocriptine (which has serotonergic effects, too) and pergolide? And then there is selegiline, but I'd think a pure agonist would be a better choice.
Use whatever works and has a reasonable margin of safety, I know I'd think long and hard about putting l-dopa into MY body ...
poster:Chairman_MAO
thread:306821
URL: http://www.dr-bob.org/babble/20040127/msgs/307072.html