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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by lawrence S. on May 28, 2003, at 18:52:19
The only effect that Mg has on me is it makes me narcoleptic. I even tried lowering the dose drastically and felt so tired and sleepy for DAYS after dosing. I believe it works for a lot of people but definately NOT me. Anyone know why? Is this an indication of what is wrong with my pharmacology? Comments appreciated.
Posted by Larry Hoover on May 28, 2003, at 22:22:07
In reply to Magnesium, Yuck! makes me sleepy, sleepy, sleepy, posted by lawrence S. on May 28, 2003, at 18:52:19
> The only effect that Mg has on me is it makes me narcoleptic. I even tried lowering the dose drastically and felt so tired and sleepy for DAYS after dosing. I believe it works for a lot of people but definately NOT me. Anyone know why? Is this an indication of what is wrong with my pharmacology? Comments appreciated.
I never came across this effect in the literature, yet I get it, and many others, too. I don't know the answer, but I'm going to look for one.
Lar
Posted by Caleb462 on May 28, 2003, at 23:42:59
In reply to Magnesium, Yuck! makes me sleepy, sleepy, sleepy, posted by lawrence S. on May 28, 2003, at 18:52:19
> The only effect that Mg has on me is it makes me narcoleptic. I even tried lowering the dose drastically and felt so tired and sleepy for DAYS after dosing. I believe it works for a lot of people but definately NOT me. Anyone know why? Is this an indication of what is wrong with my pharmacology? Comments appreciated.
I get it also, kind of. Not too terribly much. I notice if I take Mg on an empty stomach I don't get the effect. If I take it with food I do seem to get the effect, but only if it's a full 400 mg - and I find it kind of pleasant, as long as I don't have anything to do. If I don't wanna get sleepy, I just take half the pill (200 mg).
I take Magnesium Citrate, in case anyone was wondering.
Posted by samplemethod on May 29, 2003, at 6:21:44
In reply to Re: Magnesium, Yuck! makes me sleepy, sleepy, sleepy, posted by Caleb462 on May 28, 2003, at 23:42:59
Have you guys tried different chelates or magnesium formulas... do you really think they make a difference. Do you really think that the aspartate version of MG is bad as is stated below? This site seems ok, but nothing much is bscked up, and is overall kinda dodgy....so thats why im sorta skeptical about the statements about Magchelates
ANyway what are your thoughts or experiences with different mag mixes.
samplM
_______________________________________
http://www.coldcure.com/html/dep.html#cautionMagnesium Compounds That Work, That Are Ineffective, or That Injure
ON A PRECAUTIONARY NOTE, several amino acid chelates of magnesium (magnesium aspartate, magnesium glutamate and magnesium taurate) MUST be avoided in treating depression. Each of these amino acid complexes of magnesium has been reported to worsen depression. Aspartate and glutamate act as neurotransmitters in the brain and retina by facilitating the transmission of information from neuron to neuron. Too much aspartate or glutamate in the brain kills certain neurons by allowing the influx of too much calcium into the cells. This influx triggers excessive amounts of free radicals, which kill the cells. The neural cell damage that can be caused by excessive aspartate and glutamate is why they are referred to as "excitotoxins." They "excite" or stimulate the neural cells to death. Aspartate is a principal ingredient in the maligned Aspartame sweetener. To avoid aggravating depression with super-sweeteners, instead use Stevia.On the other hand, glycine or glycinate, another amino acid chelate, has been successfully used to treat bi-polar illness. Supplemental use of glycine at levels of 1 to 3 grams per day has been suggested as useful in the treatment of certain forms of bi-polar depression (manic depression). Possibly, magnesium glycinate has a double-whammy effect in depression.
> > The only effect that Mg has on me is it makes me narcoleptic. I even tried lowering the dose drastically and felt so tired and sleepy for DAYS after dosing. I believe it works for a lot of people but definately NOT me. Anyone know why? Is this an indication of what is wrong with my pharmacology? Comments appreciated.
>
> I get it also, kind of. Not too terribly much. I notice if I take Mg on an empty stomach I don't get the effect. If I take it with food I do seem to get the effect, but only if it's a full 400 mg - and I find it kind of pleasant, as long as I don't have anything to do. If I don't wanna get sleepy, I just take half the pill (200 mg).
>
> I take Magnesium Citrate, in case anyone was wondering.
Posted by Larry Hoover on May 29, 2003, at 9:14:50
In reply to Magnesium, Yuck! makes me sleepy, sleepy, sleepy, posted by lawrence S. on May 28, 2003, at 18:52:19
> The only effect that Mg has on me is it makes me narcoleptic. I even tried lowering the dose drastically and felt so tired and sleepy for DAYS after dosing. I believe it works for a lot of people but definately NOT me. Anyone know why? Is this an indication of what is wrong with my pharmacology? Comments appreciated.
I've searched high and low, and I've never seen this effect mentioned in the literature....but many of us are reporting this effect.
I called the Magnesium HelpLine: 1-800-508-8059.
(The HelpLine is run by the Magnesium Information Center, which is part of the New York Weill Cornell Medical Center. The Magnesium Information Center is overseen by the Magnesium Advisory Board.) They'd never heard of it happening.Anybody want to write a paper, and submit it for publication?
Lar
Posted by samplemethod on May 29, 2003, at 13:32:28
In reply to Re: Magnesium, Yuck! makes me sleepy, sleepy, sleepy, posted by samplemethod on May 29, 2003, at 6:21:44
Hey Lar, what is your opinion on different Mag formulas....u have any knowledge/research about them?
It follows from the post below
Thanks
> Have you guys tried different chelates or magnesium formulas... do you really think they make a difference. Do you really think that the aspartate version of MG is bad as is stated below? This site seems ok, but nothing much is bscked up, and is overall kinda dodgy....so thats why im sorta skeptical about the statements about Magchelates
>
> ANyway what are your thoughts or experiences with different mag mixes.
>
> samplM
> _______________________________________
> http://www.coldcure.com/html/dep.html#caution
>
> Magnesium Compounds That Work, That Are Ineffective, or That Injure
> ON A PRECAUTIONARY NOTE, several amino acid chelates of magnesium (magnesium aspartate, magnesium glutamate and magnesium taurate) MUST be avoided in treating depression. Each of these amino acid complexes of magnesium has been reported to worsen depression. Aspartate and glutamate act as neurotransmitters in the brain and retina by facilitating the transmission of information from neuron to neuron. Too much aspartate or glutamate in the brain kills certain neurons by allowing the influx of too much calcium into the cells. This influx triggers excessive amounts of free radicals, which kill the cells. The neural cell damage that can be caused by excessive aspartate and glutamate is why they are referred to as "excitotoxins." They "excite" or stimulate the neural cells to death. Aspartate is a principal ingredient in the maligned Aspartame sweetener. To avoid aggravating depression with super-sweeteners, instead use Stevia.
>
> On the other hand, glycine or glycinate, another amino acid chelate, has been successfully used to treat bi-polar illness. Supplemental use of glycine at levels of 1 to 3 grams per day has been suggested as useful in the treatment of certain forms of bi-polar depression (manic depression). Possibly, magnesium glycinate has a double-whammy effect in depression.
>
>
>
> > > The only effect that Mg has on me is it makes me narcoleptic. I even tried lowering the dose drastically and felt so tired and sleepy for DAYS after dosing. I believe it works for a lot of people but definately NOT me. Anyone know why? Is this an indication of what is wrong with my pharmacology? Comments appreciated.
> >
> > I get it also, kind of. Not too terribly much. I notice if I take Mg on an empty stomach I don't get the effect. If I take it with food I do seem to get the effect, but only if it's a full 400 mg - and I find it kind of pleasant, as long as I don't have anything to do. If I don't wanna get sleepy, I just take half the pill (200 mg).
> >
> > I take Magnesium Citrate, in case anyone was wondering.
>
>
Posted by Larry Hoover on May 29, 2003, at 14:01:54
In reply to Magnesium, Yuck! makes me sleepy, sleepy, sleepy, posted by lawrence S. on May 28, 2003, at 18:52:19
> The only effect that Mg has on me is it makes me narcoleptic. I even tried lowering the dose drastically and felt so tired and sleepy for DAYS after dosing. I believe it works for a lot of people but definately NOT me. Anyone know why? Is this an indication of what is wrong with my pharmacology? Comments appreciated.
I'm still looking for an understanding of what may be taking place. Are you using lithium? Do you have any kind of kidney disorder? Or osteopenia or osteoporosis? Have you tried taking calcium with magnesium?
I remain baffled.
Lar
Posted by Larry Hoover on May 29, 2003, at 14:27:01
In reply to Re: Magnesium, Yuck! makes me }} Larry Hoover, posted by samplemethod on May 29, 2003, at 13:32:28
> Hey Lar, what is your opinion on different Mag formulas....u have any knowledge/research about them?
>
> It follows from the post below
>
> ThanksAnything other than magnesium oxide. Whether or not the free aminos in the chelated forms have psychoactive effects may be very individual. If you're concerned, use other salts.
Magnesium Salt M.Wt. % Mg mEq/g
Sulfate [MgSO4.7H2O] 246.5 10 8.1
Chloride [MgCl2.6H2O] 203.2 12 9.8
Oxide [MgO] 40.3 60 49.6
Hydroxide [Mg(OH)2] 58.3 42 34
Citrate 451 16 13
Gluconate [.2H2O] 450 5.4 4.5
Lactate 202.5 12 9.8
(sorry, the table doesn't post right, even though I made it look OK in the editing box)mag sulphate is epsom salts
mag hydroxide is milk of magnesia (160 mg magnesium per teaspoon/5 mL)
mag oxide is only 4% absorbed, but the others are all about the same
Posted by Ron Hill on May 29, 2003, at 21:33:54
In reply to Magnesium, Yuck! makes me sleepy, sleepy, sleepy, posted by lawrence S. on May 28, 2003, at 18:52:19
Hi Lawrence,
> The only effect that Mg has on me is it makes me narcoleptic. I even tried lowering the dose drastically and felt so tired and sleepy for DAYS after dosing. I believe it works for a lot of people but definately NOT me. Anyone know why? Is this an indication of what is wrong with my pharmacology? Comments appreciated.
Mg makes me tired also. My solution is to take it at bedtime. I take 800 mg (measured as Mg) per night. It is a great sleep aid and also seems to help my brain chemistry. However, the bedtime dosing might not work for you if you are experiencing sleepiness DAYS later.
-- Ron
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