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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by ace on April 19, 2003, at 0:25:50
OK, 3 weeks before the holidays I begin weaning off Nardil. 10 days drug-free (except bezos and maybe Lithium) the I start Clomipramine.
I will have to start very slowly - 3 or 4 days on 12.5mg, and maybe with concomitant anxiolytic therapy (ie Buspar maybe). The reason being, Clomipramine made my derealization extremely worse after 25mg last time. But the fact that it makes me initially worse is a good sign - it's just gritting it out (but I'll have my anxiolytics with me)
My rationale for choosing Anafranil...
1. The only clinical trial of a drug for depersonalization syndrome (which I have) is with Clomipramine. This trial, albeit only small, showed Clomipramine was effective for Depersonalization Syndrome.
I have also read positive anecdotal reports of Clomipramine used for this.2. My OCD is very severe, and I need a strong treatment for it. Nardil really is a 3/4th line treatment for OCD. I used Nardil for manly depersonalisation (which it helped) and phobic anxiety (also helped) - I just was very hopeful it would kill OCD - but it didn't (Although it did provide some relief).
My target dose of Clomipramine will (initially) be 175mg - 200mg.Any comments welcome.
Ace.
PS I believe I am making the right decison Clomipramine over Nardil/Zyprexa. I think I really have to explore my options before adding an antipsychotic.
Posted by Caleb462 on April 19, 2003, at 1:38:14
In reply to The Decision is 90% made, posted by ace on April 19, 2003, at 0:25:50
What about benzos? Have you tried them already?
From what I've read, benzos tend to be the best meds for depersonalization
Posted by falconman on April 19, 2003, at 7:07:10
In reply to Re: The Decision is 90% made, posted by Caleb462 on April 19, 2003, at 1:38:14
Hi,
Klonopin + Celexa is supposed to be the best combo for DPD, maybe with some added Lamotrogine. I have DPD too, and Klonopin has helped. As it happens I'm thinking about trying Nardil now. Clomipramine did nothing for my DP. Research shows that Clomipramine doesn't work for DPD disorder very frequently, but when it does it more or less kicks ass. So if it works for you and takes down the OCD at the same time that'll be sweet. Good luck dude.
I can't help think that you were on a good thing with the Nardil. I know you won't be satisfied till you get rid of OCD too, but didn't it do wonders for your DP,Depression,SP? Are you sure you want to give that up? Is there definitely nothing else left thats worth trying with the Nardil? Sorry for raising these questions you've probably been ruminating over for hours, but I generally think that if you find a drug that works very effectively for at least half your problems than stick with it. Maybe thats only my philosophy because I can't find many drugs that help, I dunno. If you've made the decision, stick to your guns. I suppose you'll never know if you don't try.
Good luck
Peace
Mark
Posted by Tepiaca on April 20, 2003, at 21:23:30
In reply to The Decision is 90% made, posted by ace on April 19, 2003, at 0:25:50
wow Ace , you are leaving Nardil¡¡ It sounds rare
coming from you.I cant believe it , but I can see
is for a good reason.
Stay away from AP , its better to try another drugs first . AP must be the last option.
Good luck in your new journey
Tepiaca
Posted by lawrence S. on April 20, 2003, at 23:46:55
In reply to The Decision is 90% made, posted by ace on April 19, 2003, at 0:25:50
Luvox works too! My pdoc put me on higher than recomended doseage. You have to get a EEG because there is a danger that it can effect your heart rythym at this high over maximum dose. My pdoc said that according to a study, going over the reccomended dose improved ocd syptoms dramatically. I can find out more from him if you want. I think I was up to 375 or 400 mg.
Posted by ace on April 21, 2003, at 21:47:40
In reply to Re: The Decision is 90% made, posted by falconman on April 19, 2003, at 7:07:10
> Hi,
> Klonopin + Celexa is supposed to be the best combo for DPD, maybe with some added Lamotrogine. I have DPD too, and Klonopin has helped. As it happens I'm thinking about trying Nardil now. Clomipramine did nothing for my DP. Research shows that Clomipramine doesn't work for DPD disorder very frequently, but when it does it more or less kicks ass. So if it works for you and takes down the OCD at the same time that'll be sweet. Good luck dude.
> I can't help think that you were on a good thing with the Nardil. I know you won't be satisfied till you get rid of OCD too, but didn't it do wonders for your DP,Depression,SP?With depression...Oh yeah, and it still is. With DP, at first, but lately NO. Some periods are very hard...I have sit at the back of lecture halls in case of an attack. For instance, it was overcast today (this heightens the derealization feeling) and it took me 25 mins to walk a 5 min distance to uni...very sad. I don't think the Lithium is causing this but to rule it out it has been discontinued. But the DR it's mostly during phobic times. Nardil is still much better than Zoloft was ever. I have subclinical SP and it's something I believe is much less important than DP and OCD.
Are you sure you want to give that up? Is there definitely nothing else left thats worth trying with the Nardil?This is the thing that's really burning me dude...IF ONLY I could add Anafranil or certain other ADs to Nardil. I tried Pindolol with Nardil - made me worse. Lithium done zilch.
Klonopin is impossible to get in Australia unless you have neurologically proven epilepsy. All the mood stablizers are hard except Tegretol...and that is contraindicated. The only option with Nardil is Zyprexa or Risperidone. And I seriously cotemplated them. But they'll remain last line.
Sorry for raising these questions you've probably been ruminating over for hours,You are right on the money with that comment!!
but I generally think that if you find a drug that works very effectively for at least half your problems than stick with it. Maybe thats only my philosophy because I can't find many drugs that help, I dunno. If you've made the decision, stick to your guns. I suppose you'll never know if you don't try.
That's true. And if something doesn't work out...hey I'll just go back to Nardil.
Update Mark - I'll be trying PARNATE instead of Anafranil.
> Good luck
> Peace
> MarkThanks brother for all your comments. You look after yourself.
Ace.
Posted by ace on April 21, 2003, at 23:27:53
In reply to Re: The Decision is 90% made » ace, posted by Tepiaca on April 20, 2003, at 21:23:30
Posted by Tepiaca on April 23, 2003, at 5:32:34
In reply to My penis will be out of control off Nardil!!!!!!!! (nm) » Tepiaca, posted by ace on April 21, 2003, at 23:27:53
This is the end of the thread.
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