Psycho-Babble Medication Thread 208531

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Re: not crazy crazy, half-life of Zoloft » Tabitha

Posted by wcfrench on April 3, 2003, at 9:52:53

In reply to Re: day/night cycle » wcfrench, posted by Tabitha on April 3, 2003, at 2:40:10

:)
No I'm not crazy. (Well, who isn't) But not in that sense. Have you ever been to Fremont Street? It's in downtown Las Vegas, and it's the coolest place I've ever been to. I have stayed on the strip in the Luxor (pyramid)casino and walked the strip and it just doesn't compare to Fremont street. There is a light show with music every hour, the street is closed off to drivers, and all the casinos down there have better odds and cheaper food. I ate the Graveyard special new york steak, eggs, toast, hash browns for $2.99 about 4 nights in a row. The casino I stayed at had 2-deck blackjack and the one next door 1-deck!

Anyway, if you've been to the "Fremont Street Experience" you would understand why I was dancing. Only a few people do it though, and circles tend to gather. My friends were around me encouraging my singing for money, but that was later at night, just having fun.

... SpreadDaAloha thanks for your info. I should look it up and see if it makes any difference. I was led to believing this because when I was on Effexor XR, my doc indicated that if I feel depressed/apathetic at a later point in the day to take another 37.5 mg, and I did notice a difference. ... upon looking it up now, I see that the half-life of Effexor is about 5 hours and Zoloft is about 26, so you're right about that, an afternoon dosage shouldn't matter. I wonder if it has something to do with what I took the day/night before? Lamictal has a half-life anywhere from 12 to about 25 hours, averaging about 15 hours if you're on other meds. (Except meds that increase the effect; valproic acid) I take Lamictal twice a day as indicated, so it doesn't seem as if it would have anything to do with that. Klonopin's half-life is "19 to 50" hours with the onset of action lasting about 8-12 hours in adults. I guess I'll just have to take it slowly, changing one thing at a time. It's so frustrating when you are trying to desperately fix a problem that inhibits your life. Sorry for the superfluous post, hope someone benefited from the info. Thx all.

Take care,
Charlie

References--
Klonopin: http://neuro-www.mgh.harvard.edu/forum/PanicDisordersF/1.16.991.40AMKLONOPIN.LittleKn

Lamictal: http://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/CPS-%20Monographs/CPS-%20(General%20Monographs-%20L)/LAMICTAL.html
http://www.labcorp.com/datasets/labcorp/html/chapter/mono/td037700.htm

Zoloft: http://www.mentalhealth.com/drug/p30-z02.html

Effexor: http://www.join-the-fun.com/effexor-withdrawal.html (with info about Effexor's tough withdrawal period)

 

Re: not crazy crazy, half-life of Zoloft » wcfrench

Posted by Tabitha on April 3, 2003, at 13:10:28

In reply to Re: not crazy crazy, half-life of Zoloft » Tabitha, posted by wcfrench on April 3, 2003, at 9:52:53

thanks for the tip, next time I'm in Vegas I'll check out Fremont St.

(casting about for some way to get back on-topic)... um, good luck with those meds! and thanks for the links.

 

Evening blues » wcfrench

Posted by Ritch on April 3, 2003, at 22:23:58

In reply to Re: Mom, and my vacation » Barbara Cat, posted by wcfrench on April 3, 2003, at 0:13:19

> Drastic change of subject- I just got back from a week in Vegas. I was dancing in the street literally with the music loud, usually by myself, and provided much entertainment for those around me. I even set up a quarter bucket outside the hotel and tried to sing for money, but I only made $1.25 because most people knew it was a joke. Most days were great.. the pattern seems to be a great daytime (100mg Lamic, 100mg Zoloft) then things seem to get worse as the day draws to a close (or it gets dark, I can't figure out if it just has to do with the night time).. 100mg Lamic, .5mg Klonopin afternoon/night. I altered it slightly by adding 50mg Zoloft in the afternoon and .5 Klonopin in the morning to try and "balance out" what I took in the morning and at night, and it seemed to help. But I still feel better in the morning/day than I do at night. The fearful depression returns, and I can't figure out how to get rid of it. I might try some mid-day meditation. The book "Meditation as Medicine" has been working wonders for me, literally. Any suggestions or related experiences with the day/night cycle? Moon?? Who knows. Just wondering if someone has experienced this. As my first doc said when I was on a complicated cocktail, "if you tell me you feel a certain way, I believe you and don't question why, since there are so many possibilities. We just work from there."
>
> Take care,
> Charlie

Charlie, I know what you are talking about. I always feel bright and alert in the mornings and then the evenings start to get "wicked" when I am prone to be depressed. It's difficult to describe.. an existential "blackness", an apathy and simultaneously a feeling of dread. Just a thought here, but you take your Lamictal twice daily, once in the AM and then again at bedtime, right? From what I understand, Lamictal can be taken once daily (for epilepsy anyhow). If that is the case, then you could take your first dose in the AM, then take the 2nd dose say 8 hrs later in the early evening. Might make a difference. I also found Trileptal to alleviate that ickiness also.

 

For Charlie.....

Posted by Krissy P on April 5, 2003, at 23:22:27

In reply to Evening blues » wcfrench, posted by Ritch on April 3, 2003, at 22:23:58

Hi, your Vegas trip would have certainly entertained me and I would have been rooting for ya! Good for you for "making" such a great time!
However, I know how you feel here. I wish this was the Psychological Babble board because I want to ask you something about this>> "then things seem to get worse as the day draws to a close (or it gets dark, I can't figure out if it just has to do with the night time)"


The same thing happens to me. I remember that when I was little, I always hated the dark so bad, and I always slept with a night light on, and yep I admit it, I still do at 32 sometimes. lol
BUT, May I ask if you think there are some sort of feelings assocuated with your mood and why the sadness comes on at night time? Not suggesting anything, by any means, just really wondering like home life at night when you were young? Bedtime when you were young, anything? I ask because I was a "latch key" kid many, many afternoons when my parents first got divorced and even 19 years later, the AFTERNOONS at times, depress me. I feel good in the AM and
pretty ok at PM, but by my own thinking, I think my "depression in the afternoon" may have something to do with these feelings that I experienced years ago.
Anyway, this is just a thought, I truly believe in my point I'm trying to make here, (probably because I studied psychology-go figure)and it sounds like you have a great doc-that's great.
I would be happy to share what meds I'm on -just let me know:0)
All the best,
Kristen
--------------------------------------------------------------------------------------------------

Drastic change of subject- I just got back from a week in Vegas. I was dancing in the street literally with the music loud, usually by myself, and provided much entertainment for those around me. I even set up a quarter bucket outside the hotel and tried to sing for money, but I only made $1.25 because most people knew it was a joke. Most days were great.. the pattern seems to be a great daytime (100mg Lamic, 100mg Zoloft) then things seem to get worse as the day draws to a close (or it gets dark, I can't figure out if it just has to do with the night time).. 100mg Lamic, .5mg Klonopin afternoon/night. I altered it slightly by adding 50mg Zoloft in the afternoon and .5 Klonopin in the morning to try and "balance out" what I took in the morning and at night, and it seemed to help. But I still feel better in the morning/day than I do at night. The fearful depression returns, and I can't figure out how to get rid of it. I might try some mid-day meditation. The book "Meditation as Medicine" has been working wonders for me, literally. Any suggestions or related experiences with the day/night cycle? Moon?? Who knows. Just wondering if someone has experienced this. As my first doc said when I was on a complicated cocktail, "if you tell me you feel a certain way, I believe you and don't question why, since there are so many possibilities. We just work from there."
Take care,
Charlie

 

Re: For Charlie..... » Krissy P

Posted by wcfrench on April 7, 2003, at 0:43:54

In reply to For Charlie....., posted by Krissy P on April 5, 2003, at 23:22:27

Thanks Krissy

I don't know exactly where or what it stems from. It seemed to be different last month or the month before, I would feel a little better as the day went on and on, so I don't think it has to do with any past issues. I do remember, when I was in school, having very busy days and then cross country practice, and then coming home to "crash," so I would usually feel worse in the evenings. But I think that was mainly physical/mental reactions, and an overall pooped state of mind. Lately, this definitely seems to be medicine related. I can be depressed and definitely not depressed throughout different times in the day, and it follows this pattern. As Bipolar II, I am wondering if the Lamictal + Zoloft is a danger to triggering depression (as antidepressants sometimes do after using them for some time.) Before Lamictal, I took 1000mg daily of Depakote and was very stable, but had sort of a negative disposition about things (though pretty much completely stable), but the feelings I had, though very much tolerable, still prompted me to believe that possible Lamictal would be a better option for me for its antidepressing effects. The first weeks of the titration were great, but I noticed decreased effectiveness going from 50 to 100 daily, and not much change from 100 to 200. It seems that when I go for longer periods without it ('it' meaning my morning dose of Lam, Zoloft) that I hold out in a positive mood for a pretty good while. I could be on too much, or might need to decrease and add another mood stabilizer and maybe drop down the Zoloft since they can be dangerous for bipolars. I've heard good things about Trileptal (Tradazone's brother w/less side effects) so I may inquire about that. I'm holding, but not shining, and I will try anything before atypical antipsychotics because, though effective, I've been down that route and they are just too much for me. Strong and great if they work, terrible if they don't work right, and most doctors err on the side of caution about long-term use.

I am confident in the effects of mood stabilizers though, and before I didn't know any better. I worry about caffeine and klonopin because I think a caffeine high and low can cause some negative feelings, and perhaps taking more klonopin could cause it as well. I just need to ride it out. I'd love to hear your history of meds, successes and failures. It always helps to get another's perspective. Thank you so much for your concern.

Take care all,
Charlie

 

Add Lamictal, subtract Zoloft ???

Posted by wcfrench on April 8, 2003, at 16:42:26

In reply to Re: For Charlie..... » Krissy P, posted by wcfrench on April 7, 2003, at 0:43:54

When I used to take Effexor, I got more depressed at higher dosages, I think due to Bipolar II qualities. I have been increasing Lamictal and it seems to be the same calming effect but also a slight bit of depression. DO you think the Zoloft should be decreased due to the anti-depressant effect of the Lamictal? I WANT TO BELIEVE. How are ya'll doing? Thanks for your advice.

Take care,
Charlie

 

Mom, Vacation Part II (and day/night cycles)

Posted by Barbara Cat on April 17, 2003, at 11:29:23

In reply to Re: Mom, and my vacation » Barbara Cat, posted by wcfrench on April 3, 2003, at 0:13:19

Hi All,
Just got back from the second leg of Mom's death journey. This time it was hard WORK, schlepping furniture around, estate sale of her things (actually fun!), little sleep, walking out of our family home for the last time, saying goodbye forever to the places of my childhood. I was not on the euphoric high of the first trip which was due no doubt to endorphins saving my sanity from the shock. This was pure adrenaline pushing through it. My poor adrenals!

So glad to be back home and so are our 8 kitties who missed us. Life has been on hold for months and now it's time to begin a new stage of life. I'm ready - I think.

Charlie, thanks for your words of comfort. I am SO GLAD I've been working with Power of Now during this time. I saw my sister-in-law go more nuts during it and recognized the spin caused by ego and time identification. It was very difficult not to get sucked into it and those times I was sucked in were the most difficult. I will get "Meditation as Medicine". I recommend "Breathwalk" by Khalsa as well. Dance on, bro'. Have you been to Burning Man?

Day/Night cycles: I seem to be opposite of you all in this regard. I feel a sense of dread shortly after waking and begin to feel much better as evening comes on. I love the cozy glow of lights. I get a burst of energy around 8:00pm. My circadian cycles are definitely screwed. When I'm depressed I feel better in cloudy gray weather than sunny chipper days. I come alive in storms and blustery weather.

There is a certain time in the afternoon that I feel the worst. Emily Dickenson wrote a poem about 'that certain slant of light' describing her own depressions and the late afternoon light. I noticed it very strongly while back on the East Coast recently. Perhaps it was triggering my less than happy childhood, but it was also an almost physical reaction to the different play of light and shadow that caused dread and claustrophobia. William Styron talks of this phenomenon as well.

I've heard that cortisol cycling can be the reason for these mood changes during the day. I'm taking melatonin to try regulating this weird sleep cycle but I've always been like this. Becoming a night shift worker is out. Too many weirdos going about their business. - Barbara

 

Re: Lamictal - how long does it last for you?

Posted by wcfrench on April 19, 2003, at 1:28:45

In reply to Mom, Vacation Part II (and day/night cycles), posted by Barbara Cat on April 17, 2003, at 11:29:23

I take 200mg around noon and it seems like later on at work (around 6 or 7) it starts to wear off. Not the high the Lamictal gives you, I don't experience that anymore, but just the effects. I start to feel "bipolar" again and become paranoid and sensitive. Does anyone else have to take it twice a day in as little as 6-7 hour increments to keep it going? The only other thing I take in the morning is Zoloft, and I think that wouldn't wear off during the day. Any suggestions? My nights are really struggling...

Thanks all,
Take care,
Charlie

PS welcome back BCat!

 

Re: Lamictal - how long does it last for you?

Posted by SpreadDaALoha on April 19, 2003, at 3:41:49

In reply to Re: Lamictal - how long does it last for you?, posted by wcfrench on April 19, 2003, at 1:28:45

I take 150mg Lamictal in morning and 150mg at night. I don't really notice any particular part of day when it works....

 

Rate Lamictal as stabilizer

Posted by Ponder on April 19, 2003, at 12:25:23

In reply to Re: Lamictal - how long does it last for you?, posted by SpreadDaALoha on April 19, 2003, at 3:41:49

I take Lamictal 75mg in the morning and 75mg at night and do not notice much variation during the day. Well, actually, I have a lot of variation during the day, but never thought to attribute it to meds wearing off.

Question for you guys: seems most people have found Lamictal to be pretty good overall as an antidepressant. What do you think of it's stabilizing properties? My p-doc wants to add lithium. I have not had anything but trouble with lithium in the past, but he thinks it has synergy with Lamictal and wants to do another trial. I'm remembering the 45 bad drug pounds that I blessedly am no longer carrying, the awful tremor lithium gives me, etc. Arrgh. Anyway, isn't Lamictal a stabilizer? I'm already on Topa low dose (75 mg/day) for some synergy. Your thoughts?

 

Re: Rate Lamictal as stabilizer » Ponder

Posted by Barbara Cat on April 19, 2003, at 12:54:54

In reply to Rate Lamictal as stabilizer, posted by Ponder on April 19, 2003, at 12:25:23

Hi Ponder,
I recommend lithium with lamictal because of my own experience. I've run out of lithium (on purpose I think) on a few occassions and started feeling scattered and irritable within 2 days, even while on lamictal. There does seem to be a synnergy with the two and I find I have to use less of each. I was on lithium without lamictal for awhile and was not getting good antidepressant response. Adding lamictal gave me a very nice burst of energy (at first) and helped with the depression. But I've learned that for me it doesn't work without lithium which tends to smooth things out.

Of course, it's hard to say what's responsible for my overall improvement since I've had many different mixes of meds. The current one which seems to be successful is lamital 75mg, lithium 600mg, nortriptyline 75mg. The next test will be to decrease lamictal to see if I really need it since the nortriptyline made such a huge difference and along with lithium might be all I really need. We'll see.

I'm also taking thyroid since lithium can cause hypothyroidism. This is a very important and serious factor to consider. If you do go on lithium, INSIST that your thyroid levels are checked every few months. - Barbara

p.s. I had bad tremors, especially when starting nortriptyline. They went away in 2 months, thank God. I'm keeping weight down using a rebounder mini-trampoline and dancing (whether I feel like it or not!).


> Question for you guys: seems most people have found Lamictal to be pretty good overall as an antidepressant. What do you think of it's stabilizing properties? My p-doc wants to add lithium. I have not had anything but trouble with lithium in the past, but he thinks it has synergy with Lamictal and wants to do another trial. I'm remembering the 45 bad drug pounds that I blessedly am no longer carrying, the awful tremor lithium gives me, etc. Arrgh. Anyway, isn't Lamictal a stabilizer? I'm already on Topa low dose (75 mg/day) for some synergy. Your thoughts?

 

Re: Rate Lamictal as stabilizer » Ponder

Posted by wcfrench on April 19, 2003, at 13:17:27

In reply to Rate Lamictal as stabilizer, posted by Ponder on April 19, 2003, at 12:25:23

It seems to be working OK for me as a stabilizer, but not as well as Depakote did. I feel a little brighter on it, but the overall effect doesn't seem as "stabilizing" as Depakote did, but I might still have to increase the dosage, or add another mood stabilizer to reach maximum effectiveness. I am moving to Las Vegas next week and my damn doctor won't get me an appointment and won't call in a higher dosage after I keep telling him I need to go up on the Lamictal. He thinks 250mg is in the "dangerous zone" and that 400mg is only for patients with epilepsy. Damnit Jim, I'm a doctor, not a pool man. Get with it dude, I took as much as 3600mg Neurontin, I'm a high responder. I feel good after 200mg for some time, but I need more.

I know it was only recently approved (a few years back?) as a mood stabilizer, as is the trend with a few other epilepsy medications. It wasn't designed specifically for that task though, so to say that you would need an adjunct such as Lithium or Depakote to achieve maximum effectiveness would make perfect sense. It definitely gives me an antidepressant response though, in comparison with Depakote. With Depakote, I was in a stable, though negative disposition. Maybe I should try Lithium as adjunctive therapy, but I don't want my pee to smell like salt again. :-D And the days go by...

Once I reached the state of "OKness" and not total despair, books have proven to be my greatest therapy, no holds barred. "Meditation as Medicine", "The Power of Now", "Present Moment Awareness", and currently, "Emotional Longevity" (a really good one) have all taught me so much, in so many different ways. Very highly recommended. Drugs can only get you so far, and my lofty aspirations lead me to one day being able to function without medication, though I won't be upset if it doesn't happen. If you can read and it doesn't bother you, do it. Amazon has lots of good recommendations in these categories, and the reviews are always pretty accurate. See you guys.

-Charlie

 

Re: Wrong link - Emotional Longevity

Posted by wcfrench on April 19, 2003, at 13:20:44

In reply to Re: Rate Lamictal as stabilizer » Ponder, posted by wcfrench on April 19, 2003, at 13:17:27

This is the correct link:

"Emotional Longevity"

If that doesn't work, here is a direct one:

http://www.amazon.com/exec/obidos/ASIN/0670031852/drbobsvirte00-20

-Charlie

 

Re: Rate Lamictal as stabilizer » wcfrench

Posted by Barbara Cat on April 19, 2003, at 14:17:00

In reply to Re: Rate Lamictal as stabilizer » Ponder, posted by wcfrench on April 19, 2003, at 13:17:27

A very hearty second on the books Charlie recommends. I've read a few on his list and they've changed my life. One other thing, Charlie, you've answered why my pee smells so weird. I also pee like a racehorse (why like a racehorse, I wonder?) since taking lithium. - BCat

> Once I reached the state of "OKness" and not total despair, books have proven to be my greatest therapy, no holds barred. "Meditation as Medicine", "The Power of Now", "Present Moment Awareness", and currently, "Emotional Longevity" (a really good one) have all taught me so much, in so many different ways. Very highly recommended. Drugs can only get you so far, and my lofty aspirations lead me to one day being able to function without medication, though I won't be upset if it doesn't happen. If you can read and it doesn't bother you, do it. Amazon has lots of good recommendations in these categories, and the reviews are always pretty accurate. See you guys.
>
> -Charlie

 

Re: Lamictil is NOT a mood stabilizer » BarbaraCat

Posted by sac on January 9, 2004, at 12:38:23

In reply to Lamictil is NOT a mood stabilizer » Krissy P, posted by BarbaraCat on March 18, 2003, at 15:33:44

This is quite an old post but I am intrigued with this one because I have been having problems with Lamictal. I am Bipolar II and have been on Lamictal on and off (Love/Hate relationship) for the last 2 years. Sometimes, I feel good especially in the beginning of treatment, However this eventually goes away and I am left feeling depressed, apathetic, irritable, and anxious. I keep going back to lamictal because it is supposed to have a good reputation for mood stabilization with good anti-depressant action (which is my main problem.)
So why then, am I feeling so DEPRESSED? Maybe I should give up the lamictal and go for the Lithium. Any suggestions/advice would be greatly appreciated.

> Krissy,
> I have to agree with Ron and Maximus here. You are not, I repeat not, on a mood stabilizer. Lamictal is tossed into that category because of it's anti-epileptic profile but it doesn't work well enough if you need something different. I know this well because I've been in a very similar place to you. I'm fine at 50mg lamictal and if I start increasing I get depressed. I'm on a tricyclic after being on all the SSRI's and SNRI's in the book. The only thing that makes everything else tie together and work is lithium. Without lithium, NOTHING works. Lithium alone does not work but it is a necessary part of my brew.
>
> I HATE taking it because it's caused my hypothyroid condition to worsen and I'm concerned about kidney problems. But I'm only taking 600mg which seems to be the magic number for me. If you have the kind of bipolar syndrome that responds best to lithium, believe me, nothing else is going to work as well. You'll continue to futz around with this med and that. They'll work for a while and then you'll get in that weird mixed hypomanic depressed place again. I can only say to give lithium a try. For what is does, nothing else does it better. After many off/on attempts I am now a greatful believer that sometimes those old fashioned meds work the best - at least for me. As far as the weight, I now feel so much better (since starting nortriptyline) that I'm inspired to exercise like mad and am getting in better shape than ever.

 

Re: Lamictil is NOT a mood stabilizer

Posted by eugenia on January 10, 2004, at 7:31:46

In reply to Re: Lamictil is NOT a mood stabilizer » BarbaraCat, posted by sac on January 9, 2004, at 12:38:23

Hi:
I had the same experience with Lamictal. Initial buzz, then depression, fatigue and PANIC. I don't think a lot of doctors know that the stuff can make a person panic. I was really disappointed, because I heard such great things about lamictal, I thought it might be my magic bullet. Oh well. Just remember to take your side effects seriously, even if they are not the norm.

 

Re: Lamictil is NOT a mood stabilizer

Posted by Sooshi on January 10, 2004, at 9:46:05

In reply to Re: Lamictil is NOT a mood stabilizer » BarbaraCat, posted by sac on January 9, 2004, at 12:38:23

Lamictal did not work for me either. Nada. Nothing.

 

Re: Lamictil is NOT a mood stabilizer

Posted by SLS on January 10, 2004, at 9:57:31

In reply to Re: Lamictil is NOT a mood stabilizer, posted by Sooshi on January 10, 2004, at 9:46:05

If there is one thing that Lamictal is not, it is an acute anti-manic agent. It did not prevent me from having a manic reaction to changes made in my medication. However, I have read things that indicate it helps reduce rapid-cycling. When combined with lithium, it seems to. Lamictal definitely acts as a prophylactic against future depressive episodes according to the most recent studies I have read.


- Scott

 

Re: Lamictil is NOT a mood stabilizer » sac

Posted by wcfrench on January 10, 2004, at 11:36:44

In reply to Re: Lamictil is NOT a mood stabilizer » BarbaraCat, posted by sac on January 9, 2004, at 12:38:23

What else are you taking? I'm still on Lamictal since I wrote in that post (although I don't feel as good) and I have also noticed that Lamictal without another mood stabilizer doesn't quite keep me completely stable. Tell me what else you are taking and I'll write back as soon as ya do.
Take care,
Charlie

 

Re: Lamictil is NOT a mood stabilizer

Posted by Maxime on January 10, 2004, at 16:24:07

In reply to Re: Lamictil is NOT a mood stabilizer » BarbaraCat, posted by sac on January 9, 2004, at 12:38:23

It is a mood stabiliser if you look at the chemical properties of the med. It's similar to tegretol which is used as a stabiliser. It's also been approved by the FDA as a stabiliser.

Um, having said that it made me more depressed when I was on it (BP 1).

Maxime

LAMICTAL

Na+ channel inhibition
GLU decreased
Ca2+(N) channel inhibition
Ca2+(P) channel inhibition

 

Re: Lamictil is NOT a mood stabilizer » SLS

Posted by Flipsactown on January 10, 2004, at 16:27:15

In reply to Re: Lamictil is NOT a mood stabilizer, posted by SLS on January 10, 2004, at 9:57:31

Scott,

I know this is off the mark, but it appears you have been around this forum a long time, so I value your opinion. Recently my pdoc gave me an rx for 300mg daily of lithium to add to my cocktail of prozac, remeron and lamictal. Although this combo does an excellent job in relieving my depression, I do notice that my depression comes back big time around 3PM-5PM. So, I am depressed until I take my remeron at bedtime. Consequently, I have been taking my remeron earlier and earlier to get some relief. Do you think that adding lithium will get me through the late afternoon? What are your thoughts?

FST

> If there is one thing that Lamictal is not, it is an acute anti-manic agent. It did not prevent me from having a manic reaction to changes made in my medication. However, I have read things that indicate it helps reduce rapid-cycling. When combined with lithium, it seems to. Lamictal definitely acts as a prophylactic against future depressive episodes according to the most recent studies I have read.
>
>
> - Scott

 

Re: For many people, it does have MS properties.

Posted by brussell on January 10, 2004, at 17:22:16

In reply to Re: Lamictil is NOT a mood stabilizer » SLS, posted by Flipsactown on January 10, 2004, at 16:27:15

I agree that Lamictal's effect is subtle, and I doubt it would be enough for anyone with BPI.

I have "cyclical depression" (like BPII without hypomania--cycles from dysthemia down through the seven levels of hell and back).

For me, Lamictal tends to prevent depressive episodes from spiraling out of control, and it seems to have mild AD properties. I added 25mg/day of it to the 50mg/day of Parnate I take, and it seems to improve my mood and prevent evening crashes when the Parnate wears off.

Parnate's really interesting in that respect. For me it "kicks in" soon after I take it and then the AD effect wears off until the next dose--completely unlike most ADs.

 

Re: Troubles with Lamictal

Posted by sac on January 10, 2004, at 17:24:30

In reply to Re: Lamictil is NOT a mood stabilizer » sac, posted by wcfrench on January 10, 2004, at 11:36:44

I am only taking Prozac 20mgs. now. I quit Lamictal 3 days ago but am still undecided as to what I should do. I was on Lamictal in the past for about 18 months straight and while it did keep the major depressive episodes as bay, it did so by keeping me in a low grade depressive,apathetic state. The trouble is, I only really was bothered by this feeling in the evening. In the mornings, I felt OK. I was wondering whether this had to do with the way the med is metabolized. I am very frustrated. I have been on Depakote and did great for about two months until a nasty depression (side effect I believe) made me quit that. I don't know if I gave Lithium a fair chance. I only tried it for about 1 week back in August. First of all, I was scared to go on it because of the risk with toxicity and the reputation for being hard on the kidneys, thyroid, etc. Maybe this influenced my decision to quit too soon. I just remember telling my doctor that I felt more depressed on it (300mgs) he reluctantly said OK, stop it but he is not convinced that the Lithium made me feel depressed. I see him on Monday, and I am agonizing over how I am going to explain to him that I quit my medication...Again.

> What else are you taking? I'm still on Lamictal since I wrote in that post (although I don't feel as good) and I have also noticed that Lamictal without another mood stabilizer doesn't quite keep me completely stable. Tell me what else you are taking and I'll write back as soon as ya do.
> Take care,
> Charlie

 

Re: For many people ... Parnate}} Brusell

Posted by Maxime on January 10, 2004, at 19:56:04

In reply to Re: For many people, it does have MS properties., posted by brussell on January 10, 2004, at 17:22:16

Brusell - I know isn't it interesting. It has a very short half life so I suspect that is part of the reason. What I like about Parnate is that because I am bipolar, if I feel a manic episode coming on I can decrease the Parnate and I know that the decrease will have an immediate effect. It has stopped me from going into full blown mania on two occasions by doing this. No other AD will do this.

Maxime


> Parnate's really interesting in that respect. For me it "kicks in" soon after I take it and then the AD effect wears off until the next dose--completely unlike most ADs.

 

Re: Question about Bipolar disorder » Maxime

Posted by brussell on January 10, 2004, at 20:27:40

In reply to Re: For many people ... Parnate}} Brusell, posted by Maxime on January 10, 2004, at 19:56:04

> Brusell - I know isn't it interesting. It has a very short half life so I suspect that is part of the reason. What I like about Parnate is that because I am bipolar, if I feel a manic episode coming on I can decrease the Parnate and I know that the decrease will have an immediate effect. It has stopped me from going into full blown mania on two occasions by doing this. No other AD will do this.
>
> Maxime
>
>

Wow! That's VERY interesting. I don't have any experience dealing with manic phases.

I always thought the idea with mood-stabilizers was to keep bipolar people around the "center" of their mood spectrum, which hopefully was more or less normal mood.

In my case, lamictal alone just stabilized me in a dysthemic state. I really needed a strong AD, and setting off mania was never an issue.

Do mood stabilizers work as antidepressants for people with BPI and II? What do people with Bipolar Disorder do when deeply depressed? Are lithium and Depakote the only options?

Thanks a lot for any answers you can give me.


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