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Re: phenelzine

Posted by alexandra_k on March 8, 2020, at 15:18:03

In reply to Re: phenelzine paulb, posted by alexandra_k on March 8, 2020, at 15:01:13

It looks like the manufacturer of Nardil is not producing it anymore / not producing enough of it to meet supply anymore. Or... The UK NHS has decided to go with cheaper generic imports, or something, so limiting supply of Nardil. I found these:


> Store the tablets in a refrigerator between 2C and 8C. Tablets in use may be stored at normal room temperature (below 25C) for short periods (e.g. when travelling or at work).

> Each tablet contains 15 mg of the active substance phenelzine (in the form of phenelzinesulfate).The other ingredients are:mannitol, povidone, magnesium stearate, maize starch, hydroxypropylcellulose (E463), hypromellose (E464), talc, polyvinylacetatephthalate, stearic acid, sunset yellow (E110), erythrosine (E127) and titanium dioxide (E171)

2 listed manufacturers, updated 02/2017

> Storage:Store between 15 - 30C (59 - 86F)

> Each NARDIL film-coated tablet for oral administration contains phenelzine sulfate equivalent to 15 mg of phenelzine base and the following inactive ingredients: mannitol, USP; croscarmellose sodium, NF; povidone, USP; edetate disodium, USP; magnesium stearate, NF; isopropyl alcohol, USP; purified water, USP; opadry orange Y30-13242A.

> Revised Feb 2009.


> Shortage of phenelzine 15mg tablets (Nardil)

> Published 12th July 2019, updated 26th February 2020 London and South East Regional Medicines Information

> Kyowa Kirin are the sole supplier of phenelzine tablets in the UK. They are out of stock due to manufacturing issues, with no confirmed resupply date. Phenelzine tends to only be used in difficult to treat patients and many of these have been stabilised on this treatment for a long time. Given the difficulties in withdrawing treatment and initiating new treatments in patients stabilized on phenelzine it would seem advisable to maintain them on this treatment using unlicensed imports should they run out of supply. If there is potential for a patient maintained on phenelzine to run out of supply during this shortage, they should be urgently referred back to mental health specialist for advice on ongoing clinical management.

__________________________________ Notice: Nardil (phenelzine sulfate) 15mg tablets

> October 11, 2019

> Kyowa Kirin, the sole manufacturers of Nardil (phenelzine sulfate) 15mg tablets, are currently experiencing temporary disruptions.

> Kyowa Kirin, the main supplier of Nardil (phenelzine sulfate) 15mg tablets have advised a delayed resupply date of March 2020. Supplies are available from specialist importers on an unlicensed basis, and these companies listed below have advised they can continue to source unlicensed imports from abroad but the list is not exhaustive...





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