Posted by sukarno on April 3, 2010, at 9:34:28 [reposted on April 3, 2010, at 14:58:48 | original URL]
In reply to Re: OCPD and overactivity of dopamine D2/D3 receptors, posted by SLS on April 3, 2010, at 6:24:41
I think I made a mistake in posting as I read the abstract again and it only mentioned the D3 receptor. Something to do with gene polymorphisms and overactivity of D3.. a bit over my head, but I get the general idea of it. Something could be wrong with our D3 receptor.
I guess this means that Mirapex is a bad idea for treating depression or low sex drive?
I was thinking of trialling Mirapex at a low dose of 0.0625mg - 0.125mg once per day.
My other option is Zoloft, but I know that if I get on SSRIs that it will be (likely) a long term relationship and might give me another GI bleed like Prozac did. Serotonin reuptake seems to increase the risk of upper GI bleeding by 2 to 7 fold, especially if you take aspirin or other NSAIDs with it or are on anti-platelet medication.
It was suggested that taking an H2 receptor antagonist such as ranitidine (Zantac) or famotidine (Pepcid) or a proton pump inhibitor might lessen the risk. I think the study showed that it did indeed lessen the risk.
I know you can take Mirapex with Zoloft. Sometimes that is prescribed to help restore sexual function to some degree, but watch out for compulsive gambling.If we are OCPD, then perhaps Mirapex or any other D2/D3 agonist would be a bad idea?
My psychiatrist said to take Abilify and I said, "no way", so he suggested high dose Zoloft to control OCPD.
He didn't want to hear anything about non-medical strategies and said he can do all the psychotherapy himself, even though I mentioned that perhaps a counselor who specialises in OCPD might be best. "Just come to me and talk about it.. take Zoloft 50mg for the first week and then 100mg the next week". ugh.
I have held back from doing that. I wonder what Mirapex would do... would it make me excessively perfectionist?
diazepam (Valium) 5mg QID
tianeptine (Stablon) 12.5mg TID
Light therapy 3 hours/day
GNC Ultra Mega Gold vitamin supplement, BIDDx: panic disorder, MDD (unipolar, melancholia), perfectionist
poster:sukarno
thread:942019
URL: http://www.dr-bob.org/babble/neuro/20100223/msgs/942023.html