Posted by sowhysosad on September 17, 2009, at 20:53:13
In reply to Re: imipramine ) Inhibition of 5-HT Uptake Pump (%), posted by Brainbeard on September 17, 2009, at 12:43:44
> Preskorn seems to rely on different research findings than Gillman concerning imipramine's potency as an SRI.
Yeah, there's quite a bit of variation in data depending on which source you believe.
But sertraline or paroxetine always seem to come out tops in terms of SRI potency regardless of the source.
> I couldn't find comparative data on the SSRIs' affinity for 5HT including escitalopram anywhere. The claim that it has the highest affinity is all over the internet, but indeed without backup references.
It could just be people repeating Lundbeck's marketing blurb, or confusing "potency" with "selectivity".
poster:sowhysosad
thread:909605
URL: http://www.dr-bob.org/babble/neuro/20090701/msgs/917516.html