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Re: MAOI and NARI interaction

Posted by britney 27 on August 30, 2008, at 17:18:05

In reply to Re: MAOI and NARI interaction » mav27, posted by SLS on August 30, 2008, at 10:16:15

> > Ive taken nardil and reboxetine together, as well as parnate and reboxetine. I was hoping the reboxetine would raise my blood pressure but unfortunatly it just lowered it even more making the orthostatic hypotension even worse.
>
> I can't account for this. It has little, if any, NE alpha-1 antagonist properties.
>
> Did any of the following occur?
>
> * Cognitive effects: mental confusion, hypomania, hallucinations, agitation, headache, coma.
> * Autonomic effects: shivering, sweating, fever, hypertension, tachycardia, nausea, diarrhea.
> * Somatic effects: myoclonus/clonus (muscle twitching), hyperreflexia, tremor, muscle rigidity.
>
>
> - Scott

Hi Scott,

I have done a bit of "experimenting" myself. In the morning I had 4mg of Edronax and 30mg of Parnate and another 4mg of Edronax at night. I experienced a frontal headache, tachycardia and a bit of restlessness and a slight blood pressure drop. I don't know if that was a result of the fact that I accidentally had blue cheese (which I forgot was contraindicated) and whether my headache is a result of the fact that I have a bit of a cold. I will keep taking the same doses but so far I think it is quite safe. (I have actually had severe serotonin toxicity twice resulting in a coma so I am very careful). I'll report to you soon!

I did manage to find one of those preview text books on google in which I psychiatrist in America states that he gives his patients reboxetine and parnate (if the patients can get hold of reboxetine in America - I don't think it is approved yet though I have to check, maybe thats why there is little research done on the combination of the two classes).

Cheers

Britney


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poster:britney 27 thread:849082
URL: http://www.dr-bob.org/babble/neuro/20080706/msgs/849294.html