Posted by barbaracat on September 28, 2005, at 13:36:37
In reply to Re: Tyrosine vs. Phenylalanine experiences? » barbaracat, posted by neuroman on September 28, 2005, at 12:21:50
>it also has griffonia seed extract (5htp) in it. Having them both in the same formulation seems kind of counterintuitive to me.
** Thanks for the reply, Paul. I wonder if supplementing with at least some Se precursor at some point in the future isn't a bad idea since D and Se levels are inversely proportional and things might get lopsided. But if you have a negative reaction to Se have you ever looked into methylation? I believe an adverse Se reaction points to over-methylation, at least as far as the Pfeiffer/Walsh material states. Their approach doesn't always make sense to me but there's some interesting ideas there.
>>As far as the DA/NE conversion pathway, I believe it's:
>
> DLPA -> tyrosine -> L-dopa -> dopamine -> NE**Yes, thanks!
>
> However, DLPA can also be converted directly into PEA (phenylethylamine). This may explain the different effect that DLPA vs tyrosine can have in some people.
>
**Have you ever tried DPA or LPA? I like the idea of hitting the PEA pathway but the problem I've encountered with DLPA is that I feel edgy on it. I've read conflicting reports as to which one is less activating - I believe it's DPA - but I want to keep the pain reducing properties and still hit the PEA. Oh shoot, maybe I should just take the DLPA and a benzo. GABA has never has done much for me and I haven't noticed much from using glycine as the precursor either. If there's any neurochemical that I'm deficient in, it would be GABA and I haven't found a way to naturally supplement it. Valerian is supposed to but it doesn't seem to work for me.I also have chronic pain from fibromyalgia and am interested in getting the right mix also.
Interestingly, I just started Adderall and noticed it improves the pain and stiffness pretty remarkably. I wasn't expecting that but have since found out that there's research going on using stimulants in fibromyalgia and finding them successful. I guess that's what the Cymbalta bandwagon is about. Although Cym has helped me for depression, I haven't noticed any pain relief. But I'm not taking very much either.
I'd appreciate any thoughts you have using natural neuropeptide precursors. - Barbara
poster:barbaracat
thread:559511
URL: http://www.dr-bob.org/babble/alter/20050924/msgs/560677.html