Posted by MoparFan91 on June 28, 2005, at 19:19:54
In reply to Re: Inositol for OCD, posted by linkadge on June 28, 2005, at 18:49:51
> Yes coffee can depleat inositol.
>I also would drink several cups of coffee at work about everyday during my breaks (they serve free coffee in the lounge).
> Inositol acts as a second messenger to the acetlycholine, serotonin, and dopamine receptors.
>These mechanisms look rather appealing. I tend to have symptoms of underfunctioning of all three of those receptors to some extent. The OCD and (to some extent) anxiety seem to be tied to the serotonin part. The emotional deadness/grayness seems to be tied to the dopamine area. And, lastly, the mental fog which I had been having from time to time seems to be connected to the acetylcholine system.
For the acteylcholine system, I'm already taking Choline (as Choline Bitartrate), which is basically a precurser. The acetyl-carnitine, which I'm also taking, helps increase acetylcholine levels as well. For serotonin support, I'm using 200mg 5-HTP nightly (maybe increasing upwards), B6 (might add/switch to P5P), Niacinamide. Some stuff I'm taking to support dopamine is Tyrosine and possibly Omega 3.
With addition of the Inositol, the acetylcholine, dopamine, and serotonin receptors should theoretically become more sensitized. This means that receptors with the extra serotonin, dopamine, and acetylcholine being created by the 5-HTP, Choline, and Tyrosine should become more senstized by the Inositol. With this, the Inositol may have a substantial compounding effect on those receptors causing improvement in symptoms.
> I think it is said to act as a second messenger in that its actions are initiated after the receptor is stimulated. The end target of an antidepressant is perhaps to activate regional glutamate release. I think inositol acts intermediately between receptor activation, and glutamate relase.
>What effect does the Glutamate aspect have?
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> Inositol itself is actully an isomer of glucose. It is sweet.
>I've licked inositol capsules before, and they taste pretty good. I've even poured them onto frozen fruit before. When I had tablets, I actually chewed them. They tasted ok.
> I used to mix it in my coffee.
>I wonder if I could mix it with my sodas, too.
> Based on my reaction with it. I would certainly start with a lesser dose. Maybe two grams/day for a two weeks, and then increase. A lot of people find it effective at less than 18g.
>I just bought a bottle of Solaray Inositol capsules from the local health food store. Each cap has 500mg of inositol, and there are 100 caps total. I'm going to use this bottle as a starter bottle and move onto the powder form as I titrate my dose upward. I'm starting with 2g TID. I won't be able to get the powder form until a week from now.
And another question. I notice that Energy Drinks like Red Bull, AMP, Full Throttle, and others have inositol in them (along with Taurine and lots of caffeine). How much Inositol is generally found in each bottle of the energy beverage?
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> Linakdge
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poster:MoparFan91
thread:519637
URL: http://www.dr-bob.org/babble/alter/20050612/msgs/520749.html