Posted by tealady on June 22, 2005, at 18:37:59
In reply to Re: also helps cognitive impairment, posted by Jakeman on June 19, 2005, at 14:47:40
> Link, thanks for the info. Quercetin also appears to reverse cognitive impairment caused by age or alchohol consumption.
> ~J
>
> Free Radic Res. 2003 Nov;37(11):1245-52. Links
>
> Reversal of aging and chronic ethanol-induced cognitive dysfunction by
> quercetin a bioflavonoid.
>
> Singh A, Naidu PS, Kulkarni SK.
>
> Pharmacology Division, University Institute of Pharmaceutical Sciences, Panjab
> University, Chandigarh-160014, India.
>
> Cognitive dysfunction, one of the most striking age-related impairments seen in
> human beings, has been correlated to the vulnerability of the brain to
> increased oxidative stress during aging process. Quercetin is a bioflavonoid
> with strong antioxidant properties. Experiments were performed to study the
> possible effects of quercetin on cognitive performance of young, aged or
> ethanol-intoxicated mice (an animal model for cognition dysfunction) using one
> trail step down type of passive avoidance and elevated plus maze tasks,
> respectively. Aged or chronic ethanol-treated mice showed poor retention of
> memory in step-down passive avoidance and in elevated plus-maze task. Chronic
> administration of quercetin (10, 25 and 50 mg/kg) for 30 days or its
> co-administration with ethanol (15% w/v, 2g/kg per orally) for 24 days
> significantly reversed the age-related or chronic ethanol-induced retention
> deficits in both the test paradigms. However, in both memory paradigms chronic
> administration of quercetin failed to modulate the retention performance of
> young mice. Chronic quercetin administration for 30 days also reversed age
> associated increase in TBARS levels and decline in forebrain total glutathione
> (GSH), SOD and catalase levels. Chronic ethanol administration to young mice
> produced an increase in lipid peroxidation, and a decline in forebrain total
> glutathione (GSH), SOD and catalase levels, which was significantly reversed by
> the co-administration of quercetin (10, 25 and 50 mg/kg). The results of the
> present study showed that chronic quercetin treatment reverses cognitive
> deficits in aged and ethanol-intoxicated mice, which is associated with its
> antioxidant property.
>
>
>OK you guys convinced me.
I ordered a multi from the chemist and put 50mg quercetin in it yesterday.
I realise not the same level as Linkage, but should help especially with the antioxidant properties and with luck maybe with depression :-)I didn't like SJW when I tried it..foget why now, woud have to search this foum I guess. Think it increased anxiety??
I read lately that SJW interferes/reduces with estrogen ..so that would increase anxiety in that way.
Hope that quercetin doesn't work the same.
If anyone is interested I'll try to find where I read that yesterday.tea
poster:tealady
thread:515377
URL: http://www.dr-bob.org/babble/alter/20050612/msgs/517203.html