Posted by jasmineneroli on November 20, 2004, at 17:15:26
In reply to Re: More on Tryptophan- does illness affect efficacy? » jasmineneroli, posted by raybakes on November 20, 2004, at 13:28:14
Hi Ray:
Yes it is rather confusing to me, if I don't have the time to really think about it.
But there are some correlations to what you quote, with my recent experience.
If the same mechanisms apply to the Herpes Simplex that causes cold sores, I think I may have induced my own inflammatory response & "flu" last week!
1) I took 750mg of L-Arginine for 2 days, because it helps with anorgasmia (due to the nitric oxide pump it causes). I have been trying to eradicate the lingering sexual s/e's from my SSRI. It had helped in the past.
2) Just prior, I had increased the L Tryptophan dose up to 1500mg for several days, to try to improve my sleep response and anxiety. I was in the middle of trying to figure out the optimal anxiolytic dose for me.
3) I had "brain zaps", got scared and dropped the dose to 1250mg and then to 1000mg.
4) Last Saturday, I awoke to find a cold sore had developed, and I felt physically achey all over. Plus very grumpy. (I have a resident Herpes Simplex in a certain spot on my lip, but I'm not prone to cold sores, maybe get one annually).
5) Took mega doses of L-Lysine (1000mg x 3 per day, that Saturday. My health food store ppl, recommend up to 3000mg per day for the first few days of a Herpes outbreak). Lysine inhibits replication of Herpes, Arginine induces it.
6) Felt even worse. Lots of body aches, headaches, fatigue, irritability for several days.
7)Increased the L-Tryptophan back up to 1500mg on Monday. Then to 2000mg on Wednesday. Felt great by Thursday. (No more Lysine after Sunday). Slept!!!
Given 1) thru' 7):
Did I create my own body inflammation by my combination of amino acids??????? I thought I had flu (which may have been the case, since I work with the public a lot).
Looking at the abstract you quoted, if the same system applies to other versions of Herpes, I may have not only caused that cold sore outbreak, but further immune response, to the point of physiological symtpoms of illness.
Aaagh! In trying to solve 2 problems (anorgasmia and an alternative to SSRI's) I may have created a 3rd!
Comments??
Jas
poster:jasmineneroli
thread:417678
URL: http://www.dr-bob.org/babble/alter/20041108/msgs/418355.html