Posted by raybakes on October 14, 2004, at 4:54:57
In reply to Re: Big news on panic » raybakes, posted by tealady on October 10, 2004, at 22:36:33
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> One cause of panic in females is over high levels of testosterone, and the panic appears to stop when the testosterone source is removed. Funny how testosterone affects some of us differently.I think androgen excess in women is frequently an insulin resistance problem - there seems to be conflicting ideas about how insulin raises androgens - one article talked about insulin overdriving the enzyme that synthesizes androgens, and the androgen - estrone/estradiol enzyme (aromatase) not being able to keep up. Another thought that insulin reduced the production of binding globulins that transport the androgens, so making more free androgens available.
Just looked up another article, and it mentions another enzyme called 5-alpha reductase that sends androgen precursors of estogens, the wrong way - instead of going from androgen to estrogen via aromatase, 5-alpha reductase sends them to another androgen pathway, and these androgens inhibit estrogen formation in the ovary. Zinc, saw palmetto, riboflavin, fennel, nettles, fenugreek are all 5-alpha reductase inhibitors.
this product looks interesting..
http://www.yourmenopausetype.com/testo-calm/
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> Also strange how the research and drugs appear to be geared to preventing testosterone to estrogen conversion, no?..as opposed to promoting the conversion <grin>. Had a look last week but couldn't find anything ...
Theres a new range of drugs to help with hormone sensitive cancers - tamoxifen inhibited the estrogen receptors, but now aromatase inhibitors are being used too, as estradiol excess is implicated in these cancers. Some recent research also implicates estradiol in prostate cancer - as men age, inflammation increases aromatase activity, converting too much testosterone to estradiol. So far the androgen DHT was thought to be the culprit, will be interesting to see if the new studies are accepted.Ray
poster:raybakes
thread:399340
URL: http://www.dr-bob.org/babble/alter/20040928/msgs/402897.html