Posted by sfy on October 2, 2004, at 10:50:06
In reply to Re: Selegiline Phenylalanine, posted by Terry on September 30, 2004, at 20:46:26
> I've been doing 10mg Selegiline and 1000mg L-Phenylalanine for about three weeks. I have a moderate persistent depression. I get a slight mood elevation from it but not very much. The problem that I have is that every few days I go into these states where I experience some kind of mental torment that makes me kind of suicidal. I was experiencing this long before taking Selegiline plus L-PA. It's just that when I go into these cyclical states this combo does nothing at all to help; but then nothing that I've taken [which includes EVERYTHING] does help with this mental agony cycle.
>
> What is really good about the combo though is that it really supresses my appitite. I've lost 15 lbs since starting on it. I've gained a lot of weight on Zyprexa (which I quit taking because it didn't help my problem.) So I really need to lose the weight.
>
> I'm just wondering if anyone else has noticed a decrease in appitite with this combination?
>
> TerrySounds like a case of double depression - a dysthymia punctuated by bouts of major depression. I haven't seen any evidence that this combo works well to alleviate or prevent deep depressive episodes. Those tend to be more serotonin related rather than dopaminergic which is how the selegiline/phenylalanine supposedly acts.
Also, some have reported better luck using DLPA rather than just LPA. There's an added effect from the DPA isomer.
I've been on 5 mg. of selegiline and 500 mg. of DLPA for about a week. Haven't noticed anything dramatic. My initial headache passed after a few days. My mood is stable but not remarkably different from before I started. I haven't noticed any noticeable difference in appetite.
If I don't see any changes, I'm going to bump up to 10 mg. of selegiline in a week's time.
poster:sfy
thread:377600
URL: http://www.dr-bob.org/babble/alter/20040928/msgs/398249.html