Posted by tendency on August 11, 2004, at 16:37:06
In reply to Re: Fish Oil » Tendency, posted by Larry Hoover on August 7, 2004, at 12:33:40
> It is apparent by your conditional invocation of anecdote that you do not have a background in biochemistry. Perhaps it would be best if I linked to a site with a reasonable overview of the relevant eicosanoid/prostaglandin chemistry, so that you can get a grounding for subsequent discussion.
>
> BTW, one cites references.lol whoa! you're way to hot a pistol for me to tangle with (as he slowly re-holsters..). ok, ok, that was on friday when i was feeling a tad manic (which often manifests as aggression). please forgive i was outta control there. :-)
>
> > > DHA has more of a direct effect on neuronal behaviour.
> >
> > Again, sources please?> > > DHA is also linked to changes in genetic regulation of neuron behaviour. There are substantial changes in genes which regulate energy metabolism, membrane protein expression, neuronal plasticity, and other beneficial changes. (See: http://www.pubmedcentral.gov/articlerender.fcgi?tool=pmcentrez&artid=122397, Table 5)
> >
> > ..perhaps that linkage can be established in *rats*..
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> Perhaps? It has *clearly* been established in rats. The very same genes are operant in other mammals, including our own selves. It is unethical to perform similar experiments on humans, and is seldom even permitted in other primates, any more. Again, I suspect that unfamiliarity with the subject matter is what leads you to suggest that the relevance in Homo sapiens is conditional.well, without trying to find some references (he he, i *am* lazy)..i would like to assert that there have been many a treatment that has worked wonderfully in lab animals only to 'go bust' in humans.. yeah, i know, kinda a week rebuttal there..sigh.
> > > There is substantial evidence that man evolved on a diet that provided an omega-6:omega-3 ratio of about 1:1.
> >
> > Such as?
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> Once again, I believe it best to provide a background information source, rather than a series of technical citations. The diet of pre-agricultural man is the issue, as compared to the highly distorted diet resulting from dependency on grain crops, and meat derived from grain-fed animals. Here is a decent review of the evidence: http://faculty.smu.edu/jowillia/berardi_paleonutrition/williams_paleonutrition.htm
>that was an interesting article and ive seem similar before. also of interest was the gentleman who proposed that ADD/ADHD could possible be viewed as a left over trait(s) from our long distant past when we needed to constantly shift our attention to avoid predation (something along those lines anyhow).
> > > There is some controversy over whether supplementing with the shorter omega-3 fatty acid alpha-linolenic (e.g. flax oil) is sufficient to overcome the imbalance from diet, as there are five chemical reactions required to convert it to DHA. The yield, the efficiency of that process, has been estimated to be close to zero in men, and no more than 7% in women.
> >
> > Source??
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> I have posted the references to this data many times already.
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> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12323085
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> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12323090
>
I think it wise, perhaps, to be weary of findings that have such a small (6) study group. Talking about the first post. Of course I don't really know what I'm talking about but intuitively it makes sense. Can that reasonably be extrapolated to the population at large? No comment on the second reference.
> I can back up my scientific presentations, be certain of that. I seldom do so, for the reasons I have elucidated above.Of that I have no doubt, good sir!
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> > Mars conjuct (sic) Venus?
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> I don't appreciate sarcasm, particularly when I have not had the opportunity to clarify earlier remarks. I will refer this comment to Dr. Bob for assessment of its civility.Yeah, I thought it was funny at the time, course, I was kinda wiggin' too..if you know what i mean.
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> > Thanks for clarification.
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> When you have done some relevant reading, I welcome further discourse.
>
> Lar
>
> Back to <vacation mode>Enjoy vacation!
poster:tendency
thread:356500
URL: http://www.dr-bob.org/babble/alter/20040718/msgs/376513.html