Posted by Ron Hill on January 5, 2004, at 13:26:09
In reply to NADH -- what are your experiences?, posted by psychlover on January 5, 2004, at 5:04:14
Hi Psychlover
> I was reading a bunch of the old posts re: NADH, esp. between Larry Hoover and Ron Hill, and at first there was raving about how wonderful it was and the next thing you know Ron is trying to get rid of his whole stash! What happened? Has anyone else had any experience with NADH?
For about eight months, ENADA NADH did a good job in treating my bipolar II atypical depression (low motivation, anergy, hypersomnia, loss of enjoyment of life, etc). I'm convinced that the antidepressive effect was due to ENADA NADH increasing my dopamine levels.
Unfortunately, ENADA NADH caused irritability which became worse as the trial progressed. In an attempt to eliminate the irritability side effect, I continually reduced the dosage and five months into the trial I was taking only one 2.5 mg tablet per week. Finally, at about the eight month mark, it became apparent that I needed to completely quit the supplement because of the irritability.
As an aside, I had a very similar response to SAM-e. It worked great for about five months and then turned me into an irritable raging maniac (GRRRRRR!!).
Right now I'm doing very well. I hope it continues. Here is my current cocktail:
300 mg/day Lithobid (moodstabilizer).
300 mg/day St. John’s Wort (provides some good antidepressant effectiveness).
L-theanine (increases dopamine and GABA, reduces cortisol; treats irritability). Currently, I take 200 mg of l-theanine PRN (as needed) to treat irritability. Lately, I have not needed to take it very often. But when I do, it calms my irritability for about five hours. Until a couple of weeks ago, I had been taking 400 mg/day of l-theanine for about seven weeks. However, I fell into a deep depressive episode, and I decided to err on the side of caution and reduce my dosage of l-theanine because some research indicates that it can reduce serotonin levels. I don’t know for fact that l-theanine contributed to my depressive episode. Perhaps I was just cycling (bipolar II).
250 mg/day of TMG.
Small pocket-full of vitamins and minerals per day (most notably, 800 mg/day of magnesium taken at bedtime to improve sleep and overall brain functioning).
Three teaspoons of Carlson’s Fish Oil per day.
Exercise (1 – 2 hours/day; reduces depression and irritability but can increase hypomania, thereby, requiring a temporary increase in the amount of moodstabilizer).
NO REFINED SUGAR!!
No alcohol (and no recreational drugs since the 70's).
Zone diet.
Best Wishes!-- Ron
poster:Ron Hill
thread:296604
URL: http://www.dr-bob.org/babble/alter/20031218/msgs/296746.html