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Fentanyl, Dilaudid and others

Posted by undopaminergic on June 6, 2022, at 9:56:35

In reply to ***More on the topic from another perspective..., posted by SLS on June 6, 2022, at 5:53:13

> Fentanyl is one of the most important drugs we have in the pharmacopia. Screw those who abuse it - and even die from abusing it. Ask the spouse of a cancer patient who is near death what they think of Fentanyl. What about people who need more than hydrocodone or dilaudid during the first few days after spinal fusion or knee-replacement surgery. Are we to ban every drug or scare the hell out of people regarding every useful drug that otherwise healthy people abuse? Cough medicine?
>
> This really pisses me off.
>
> And screw any doctor that tries to use half-life as a propaganda tool to cast a negative spin on the use of a valuable drug that he can't relate to personally.
>
>
> - Scott

Hi SLS,

I sympathise with your point of view, but I must ask why you mention Dilaudid (hydromorphone) as an example of a potentially inadequate drug. It is more potent than morphine, per unit of weight, and morphine is still considered the gold standard.

In any case, there are factors beyond potency that distinguish the different opioids from each other. This is why opioid rotation is often a workable stategy to tackle the tolerance issue, but more importantly, the choice of which one(s) to use should be tailored to the specific patient.

-undopaminergic


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