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Re: Best serotonin 5-HT2C antagonist?

Posted by Jay2112 on September 25, 2021, at 16:45:58

In reply to Re: Best serotonin 5-HT2C antagonist? SLS, posted by undopaminergic on September 12, 2021, at 8:30:01

> > Hi.
> Hi.
> > Ritanserin is probably the most selective 5-HT2 antagonist in the world. When I looked in on it a bunch of years ago, it was reported to be virtually devoid of side effects. It is a drug without an indication. It has no other purpose that I recall other than being an antidepressant augmenter. By itself, it is inert.
> >
> >
> > - Scott
> But ritanserin is not clinically available as far as I know.
> -undopaminergic

Nefadazone, available generically in the U.S.
has good 5ht2 antagonism. I found it a great drug to take possibly with an antipsychotic. Nefadazone does not feel *at all* like an SRI/SNRI.


Humans punish themselves endlessly
for not being what they believe they should be.
-Don Miguel Ruiz-




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