Posted by TH on May 16, 2019, at 17:01:02
In reply to Re: Tranylcypromine - Fluctuating Effects, posted by Christ_empowered on May 16, 2019, at 10:14:28
> hi. i dont take maoi drugs, so i cannot answer from personal experience.
>
> the late Dr.Ivan Goldberg was a fan of Parnate. His approach seems to have been one that was popular in the 60s...Parnate, if that doesn't do the trick, Parnate+dexedrine, possibly parnate+dexedrine+antipsychotic.
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> I'd be careful about making a diagnosis of bipolar of any sort based on response to a powerful maoi. having said that, depending on the sort of problems remaining, adding an antiseizure drugs, possibly maybe an antipsychotic, might be something worth talking over with your pdoc.
>
> way back when, combo pills were very common in psychiatry. one combo pill was parnate+stelazine, an older, high potency, phenothiazine-type (same family as thorazine) antipsychotic. i think it was 10mgs/Parnate + 1 mgs/ stelazine. anyway...
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> i wouldn't personally go for stelazine--higher risk of TD, lots of akathisia--but clearly there's a longstanding practice of using tranquilizers with parnate to enhance response, improve tolerability (I'm guessing it would help with stimulation and maybe add some to the overall effects, by reducing anxiety, agitation, and tension?), etc.
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> ok. hope this helps a bit.
Thanks for the reply. It's interesting to hear that so many people must have struggled with tolerability. While there certainly are some obvious side effects, I've found the relief that accompanies them to be far greater than any discomfort they bring.I'm surprised to hear that agitation is also a concern for some as I have found Tranylcypromine to be very grounding. Unmedicated, agitation is usually one of my biggest problems, however on the medication it almost completely disappears.
I think you're totally correct about it being unwise to infer some sort of bipolar disorder, or other condition, at this stage. From my current, more positive, mindset I can see that it is still far too soon to be considered at a steady state, and that there is every chance that things will change over the next few weeks / months. If this pattern did continue for a great length of time, it may be worth thinking seriously about, but at this stage it is probably not worth the worry.
That being said, I have certainly noticed that those low periods have been accompanied by an obsession with medication / diagnosis, and overthinking my mental state. So watch this space I guess.
poster:TH
thread:1104415
URL: http://www.dr-bob.org/babble/20190513/msgs/1104432.html