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Re: Tranylcypromine - Fluctuating Effects

Posted by Christ_empowered on May 16, 2019, at 10:14:28

In reply to Re: Tranylcypromine - Fluctuating Effects, posted by rose45 on May 15, 2019, at 12:41:28

hi. i dont take maoi drugs, so i cannot answer from personal experience.

the late Dr.Ivan Goldberg was a fan of Parnate. His approach seems to have been one that was popular in the 60s...Parnate, if that doesn't do the trick, Parnate+dexedrine, possibly parnate+dexedrine+antipsychotic.

I'd be careful about making a diagnosis of bipolar of any sort based on response to a powerful maoi. having said that, depending on the sort of problems remaining, adding an antiseizure drugs, possibly maybe an antipsychotic, might be something worth talking over with your pdoc.

way back when, combo pills were very common in psychiatry. one combo pill was parnate+stelazine, an older, high potency, phenothiazine-type (same family as thorazine) antipsychotic. i think it was 10mgs/Parnate + 1 mgs/ stelazine. anyway...

i wouldn't personally go for stelazine--higher risk of TD, lots of akathisia--but clearly there's a longstanding practice of using tranquilizers with parnate to enhance response, improve tolerability (I'm guessing it would help with stimulation and maybe add some to the overall effects, by reducing anxiety, agitation, and tension?), etc.

ok. hope this helps a bit.


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