Posted by Schlepo on March 27, 2019, at 18:45:43
In reply to Re: Alternatives to Olanzapine., posted by Christ_empowered on March 27, 2019, at 15:56:30
> hi. until recently, using most neuroleptics/antipschotics in depression was considered off label. i think...there's a 60s combo pill still out there, perphenazine and elavil together...i think that was approved for some rough forms of depression.
>
> anyway...what drugs has your psychiatrist talked to you about? some people need antipsychotics, at least for a while. if you can make a go of things without one...
>
> more power to you.
>
> olanzapine is somewhat unusual...i think symbyax is approved for 'treatment resistant depression,' so in that sense, its not off label to use zyprexa.
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> i think a lot of the newer 'atypicals' are approved to use with an antidepressant. seroquel...i remember reading that they'd done studies showing it could, sometimes, for some people, treat some forms of depression at a low(ish) dose...
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> but I dont know if it has fda approval as monotherapy or not. plus, seroquel can be rough. but not always.
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>Actually the only thing my pdoc has talked about is raising my olanzapine. I mentioned Rexulti, but she has no interest in new "unproven" medications. Briefly spoke about switching nortriptyline to something else, but that would require closer monitoring than she could provide (and I sort of agree there.)
poster:Schlepo
thread:1103692
URL: http://www.dr-bob.org/babble/20190206/msgs/1103709.html