Posted by linkadge on August 23, 2018, at 14:27:32
In reply to Re: carbamazepine (tegretol) for social anxiety, posted by farshad on August 23, 2018, at 8:30:58
>but my theroy is good tho right . carbamazepine
>inhibiting crh secretion from hypothalamus ..In theory yes. Reducing CRH would reduce cortisol release. But, you might find that the primary targets of the drug (i.e. sodium / calcium channel inhibition) offset this benefit.
For example, cyproheptadine is a powerful regulator of cortisol. It is given to people with cushings disease (very high cortisol). However, if you have taken it, you may find that it can be a heavy medication - leaving you feel a bit yucky with long term use. In other words, other effects of the drug, outweight the anticortisol benefits, for treating anxiety disorders.
Linkadge
poster:linkadge
thread:1100299
URL: http://www.dr-bob.org/babble/20180728/msgs/1100558.html