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Re: carbamazepine (tegretol) for social anxiety

Posted by farshad on August 22, 2018, at 16:19:11

In reply to Re: carbamazepine (tegretol) for social anxiety, posted by linkadge on August 22, 2018, at 14:15:47

> Just to add...
> Lyrica and Gabapentin are approved for anxiety in Europe. Have you considered / tried either of these meds? They are anticonvulsants and likely have a bit more efficacy in anxiety.
> Not sure if you've tried penibut (a supplement). It operates via the same mechanism as lyrica / gabapentin. If you haven't tried phenibut, you might order / try this to see if it helps your anixety. If it does, there is a decent chance that lyrica or gapapentin will help anxiety.
> If I could chose between lyrica or tegretol for anxiety, I would chose lyrica. If there was a mood disorder (i.e. bipolar) with it, then I'd go for tegretol.
> Linkadge

i have tried lyrica and it just made me sleepy. not much for anxiety tbh. phenibut didn't help anxiety either.
lyrica I think it is in same class as carbamazepine , lamictal etc

the only difference is carbamazepine from these other it happens to inhibit CRH in the hypothalamus straight from the source! You know what CRH is right? and its role in anxiety is huge!!!!!
valproate I think decreases CRH also.

but lyrica,gabapentin, lamictal etc no effect on CRH itself.

Im over the serotonin part by the way, I have found out my anxiety is caused by excess CRH-CRHR1 signaling.
high CRH causes high serotonin release especially high 5h3 signaling which explains why I feel dizzy all the time.

the only time I think my anxiety was at the lowest was when I took a low dose of zyprexa, it happens to inhibit CRH in the hippocampus, so i think there is a connection here and I have found it.

I havent started carbamazepine yet but it should be avalibale soon for me to buy.

people just look on the outside, yeah SSRI approved for anxiety cause it increases serotonin, meanwhile one important aspect of a ssri like Prozac is it increases allopregnenolone *neurosteroid which is responsible mostly for its anti anxiety effect, my point being you have to go trough studies on each drug and see what fits you the most what you think your problem is. in my case high CRH*CRHR1,rare case, not many solutions , but i found it.
carbazmepine structure is similar to imipramine and i heard that drug is good for anxiety and it inhibits crh too in the PVN!




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