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Re: Parnate and orthostatic hypotension chrismeurer

Posted by pedr on November 24, 2017, at 8:24:26

In reply to Parnate and orthostatic hypotension, posted by chrismeurer on November 23, 2017, at 12:08:12

> Hello,
>
> For those who take or have taken parnate, did you experience orthostatic hypotension? As you may know, dr. ken gillman sees the presence of orthostatic hypotension as a sign of minimum therapeutic dose.

Hi again Chris,

yes, I experienced a very clear drop upon standing and tracked it twice daily as GIllman recommends (sitting, immediate standing, standing). Unfortunately after 2 weeks of doing OK, my mood absolutely crashed into a severe depression and showed no signs of lifting. Hence I'm hot-swapping for Nardil which I've done OK on before. A lot fatter and tireder but OK :/

A couple of observations from my experience with it:
- my insomnia simply disappeared overnight at the same time the depression increased. It was pretty bad up until that point. That was about 3.5 weeks in.
- around the same time I noticed my systolic wasn't going down any more upon standing, just my diastolic which was curious.
- for 2 days I got very strong heart palpitations all day long. It took me a while to recognise it and it was surprisingly uncomfortable. But I have a lot of upper GI issues which probably worsened my perception of it.

I hope the Parnate continues to work out for you, good luck,
Pete


I love the smell of Abilify in the morning. The smell, you know that chemical smell. Smells like victory. Some day this war's gonna end...
====
Atypical Depression, OCD, IBS-C, GERD since '96


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