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Re: Add zoloft to clomipramine

Posted by linkadge on October 25, 2017, at 16:28:25

In reply to Add zoloft to clomipramine, posted by chrismeurer on October 22, 2017, at 14:39:15

I haven't heard of serotonin syndrome from the combination of serotonin reuptake inhibitors.

In theory, what you say makes sense. If the serotonin transporter is fully saturated, then Zoloft might begin to bind more to its secondary site (dopamine). Alternatively, clomipramine might also begin to bind more to it's secondary sites (norepinephrine, 5-ht2a, histamine etc).





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