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Re: Which benzo with short half life? Lamdage22

Posted by SLS on October 25, 2017, at 16:21:50

In reply to Re: Which benzo with short half life?, posted by Lamdage22 on October 25, 2017, at 10:37:52

> Hi Scott,
>
> thanks for your post. no one has. I have experience with Alprazolam. Half life is shorter than Lorazepam?


> > Has anyone already suggested Xanax (alprazolam) non-XR? Xanax has a fairly short half-life for a benzodiazepine. The average time is 11.2 hours, although this is variable interindividually. Compared to Ativan (lorazepam), Xanax usually penetrates anxiety more completely, and may have a mild antidepressant effect. Xanax can produce a greater feeling of relaxation than Ativan. One needs to beware of behavioral disinhibition with Xanax, though.

I see that lorazepam has a 12 hour half-life, which is nearly identical to alprazolaam. However, the experience of hangover may be different between the two drugs. If the binding affinity of alprazolam is higher than that of lorazepam, you might be able to use a dosage of alprazolam that is low enough to prevent an extended hangover. That's just a guess, though.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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